Results 71 to 80 of about 780,603 (289)

Patenting in Europe: The Jurisdiction of the CJEU over European Patent Law

Perspectives on Federalism, 2015
This paper will deal with EU competence over patent law, especially in the context of the TRIPS Agreement with reference to the ruling of CJEU in the Daiichi Sankyo case (CJEU case C-414/11 Daiichi Sankyo v DEMO Anonimos). The first part will explain the
Minn Mari
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

STEAM Experimental Facility: A Step Forward for the Development of the EU DEMO BoP Water Coolant Technology

Energies, 2023
Within the EUROfusion roadmap for the technological development of the European-DEMOnstration (EU-DEMO) reactor, a key point has been identified in the discontinuous operation (pulse-dwell-pulse) of the machine.
Alessandra Vannoni, Pierdomenico Lorusso, Pietro Arena, Marica Eboli, Ranieri Marinari, Amelia Tincani, Cristiano Ciurluini, Fabio Giannetti, Nicolò Badodi, Claudio Tripodo, Antonio Cammi, Luciana Barucca, Andrea Tarallo, Pietro Agostini, Alessandro Del Nevo   +14 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Thermo-Mechanical Analysis and Design Update of the Top Cap Region of the DEMO Water-Cooled Lithium Lead Central Outboard Blanket Segment

Applied Sciences, 2022
Within the framework of the EUROfusion research and development activities, the Water-Cooled Lithium Lead (WCLL) Breeding Blanket (BB) is one of the two candidates to be chosen as the driver blanket for the European DEMO nuclear fusion reactor. Hence, an
Gaetano Bongiovì, Salvatore Giambrone, Ilenia Catanzaro, Pietro Alessandro Di Maio, Pietro Arena   +4 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

The quasi-continuous exhaust regime in ASDEX Upgrade and JET

Nuclear Materials and Energy
The quasi-continuous exhaust (QCE) regime is a type-I ELM-free high confinement regime obtained at high plasma shaping and high separatrix density. A comparison with various ELM-free regimes in the literature is presented together with potential physics ...
M. Faitsch, M. Dunne, E. Lerche, P. Lomas, I. Balboa, P. Bilkova, P. Bohm, L. Gil, G.F. Harrer, A. Kappatou, D. Kos, B. Labit, L. Radovanovic, A. Redl, O. Sauter, S. Silburn, E.R. Solano, A. Tookey, E. Viezzer, E. Wolfrum, U. Stroth   +20 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Core ion measurements with collective Thomson scattering for DEMO burn control

Nuclear Fusion
DEMO burn control will require measurements of a range of plasma parameters, but the suite of feasible diagnostics for this purpose is limited. Here we assess the accuracy with which a collective Thomson scattering (CTS) diagnostic can provide key ...
J. Rasmussen, S.B. Korsholm
doaj   +1 more source