Results 61 to 70 of about 1,090 (156)

Efficacy of Compound Betamethasone Periocular Injection Combined With Oral Mycophenolate Mofetil in Active Thyroid‐Associated Ophthalmopathy: A Pilot Study

International Journal of Endocrinology, Volume 2025, Issue 1, 2025.
Objective To evaluate the efficacy of combined therapy of compound betamethasone periocular injection and oral mycophenolate mofetil (MMF) in treating active thyroid‐associated ophthalmopathy (TAO). Methods A retrospective study was conducted on 17 patients with active TAO treated with compound betamethasone periocular injection combined with oral MMF ...
Chunchun Xiao, Yiwei Liu, Wan Zhou, Yan Xing, Shandong Ye, Bin Huang, Suraiya Saleem   +6 more
wiley   +1 more source

Otolaryngologist surgical preferences for orbital decompression in thyroid eye disease: A North American survey

Laryngoscope Investigative Otolaryngology, Volume 9, Issue 6, December 2024.
While orbital decompression is recommended for severe, refractory thyroid eye disease according to the ATA‐ETA Consensus Statement in 2022, there are no clear guidelines regarding the optimal surgical approach. We conducted a survey completed by otolaryngologists that assessed pre‐operative, operative, and post‐operative management preferences for ...
Ryan C. Higgins, Ciaran F. Lane, Neerav Goyal   +2 more
wiley   +1 more source

Life-threatening complications of high doses of intravenous methylprednisolone for treatment of Graves’ orbitopathy

Thyroid Research, 2019
Background Treatment of moderate to severe Graves’ orbitopathy (GO) is based mainly on intravenous pulses of methylprednisolone. High doses of methylprednisolone can exert several adverse effects, some of which might be life-threatening. The objective of
Dorota Walasik-Szemplińska, Grzegorz Kamiński, Iwona Sudoł-Szopińska   +2 more
doaj   +1 more source

Ocular immune‐related diseases: molecular mechanisms and therapy

MedComm, Volume 5, Issue 12, December 2024.
The molecular mechanisms underlying ocular immune‐related diseases is due to the dysregulation of immune responses. The unbalanced activation of diverse immune cell types, inflammatory activators and pathways are related to the immunological pathogenesis of ocular immune‐related disease which paly an essential role of immune processes in the ...
Yakun Wang, Shangze Gao, Fan Cao, Hui Yang, Fengyang Lei, Shengping Hou   +5 more
wiley   +1 more source

Severity of thyroid eye disease and type-2 diabetes mellitus: Is there a correlation?

Indian Journal of Ophthalmology, 2020
Purpose: To study the correlation between thyroid eye disease (TED) with type-2 diabetes mellitus. Methods: A cross-sectional cohort study was conducted from Jan 2018 to Dec 2018, in patients presenting with thyroid eye disease to orbit and oculoplasty ...
Lakshmi B Ramamurthy, Viji Rangarajan, Neha Srirao, Bindu Malini, Renu Bansal, Kavitha Yuvarajan   +5 more
doaj   +1 more source

Association of clinical course with thyroid-stimulating immunoglobulin in Graves' ophthalmopathy in Mongolians.

PLoS ONE, 2022
Graves' ophthalmopathy (GO) is a complex inflammatory condition affecting the orbit and is often associated with Graves' disease (GD). This study aims to determine the levels of thyroid-stimulating immunoglobulin (TSI) and thyroid-stimulating hormone ...
Oyungerel Bayarmunkh, Chimedlkhamsuren Ganbold, Sima Das, Uranchimeg Davaatseren, Nomin-Erdene Minjuurdorj, Sarantuya Jav   +5 more
doaj   +1 more source

The association of race with thyroid eye disease presentation and outcomes

Frontiers in Ophthalmology
IntroductionClassification of thyroid eye disease (TED) is largely based on guidelines developed in Europe and North America. Few studies have investigated the presentation and treatment of TED in Black populations.
Diane Wang, Diane Wang, Diane Wang, Charlotte Marous, Charlotte Marous, Charlotte Marous, Pelin Celiker, Wenyu Deng, Wenyu Deng, Eva Kristoferson, Ali Elsayed, Roman Shinder, Roman Shinder, Roman Shinder, Nickisa Hodgson, Nickisa Hodgson   +15 more
doaj   +1 more source

The clinical tomographic interconnection in diplopia of patients with Graves' orbitopathy

Клиническая и экспериментальная тиреоидология, 2012
There was investigated the relationship between the clinical features of the diplopia in patients with the Graves’ orbitopathy and the specific signs of the orbit obtained by the multi-slice CT scanning in the study.

doaj   +1 more source

Evidence That Baseline Levels of Low-Density Lipoproteins Cholesterol Affect the Clinical Response of Graves’ Ophthalmopathy to Parenteral Corticosteroids

Frontiers in Endocrinology, 2020
BackgroundHigh dose intravenous glucocorticoid (ivGC) therapy is the first line treatment in moderate to severe Graves’ ophthalmopathy (GO) and is associated with a clinical response rate ranging from 50% to 80%.
Adriano Naselli, Diletta Moretti, Concetto Regalbuto, Maria Luisa Arpi, Fabrizio Lo Giudice, Francesco Frasca, Antonino Belfiore, Rosario Le Moli   +7 more
doaj   +1 more source

What is the aim of immunosuppressive treatment in patients with graves' orbitopathy?

, 2014
The EUGOGO criteria and the clinical activity score (CAS) have been used as outcome measures to report response rates for patients after pulsed intravenous methylprednisolone (PIM) therapy.
Wiersinga, Wilmar M., Mourits, Maarten P., Yang, Morgan, Soeters, Maarten R.   +3 more
core   +1 more source