Results 31 to 40 of about 47,994 (152)
Evolutionary hallmarks of the human proteome: chasing the age and coregulation of protein-coding genes [PDF]
Background The development of large-scale technologies for quantitative transcriptomics has enabled comprehensive analysis of the gene expression profiles in complete genomes.
Francisco José Campos-Laborie+4 more
core +3 more sources
We investigated the molecular basis of host switching by the phytophagous West Indian fruit fly (A. obliqua). Third‐instar larvae showed differential gene expression according to host plants: red mombin, mango, and carambola. The main gene categories differentially expressed were digestion, detoxification, and gene regulators.
Sandra M. Velasco‐Cuervo+5 more
wiley +1 more source
Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]
Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core +4 more sources
Life in urban areas may alter the gut microbiota and host physiology, leading to a higher susceptibility to pathogens. In contrast, specific members of the gut microbiota community have been shown to mitigate the intensity of malaria infection. House sparrows, living in close proximity to humans, are exposed to a unique environment with human‐shaped ...
Daliborka Stanković+4 more
wiley +1 more source
Three reference genomes for freshwater diatom ecology and evolution
Abstract Diatoms are an important component of marine and freshwater ecosystems. Although the majority of described diatom species live in freshwater systems, genome sequencing efforts have focused primarily on marine species. Genomic resources for freshwater species have the potential to improve our understanding of diatom ecology and evolution ...
Wade R. Roberts, Andrew J. Alverson
wiley +1 more source
Kinetic control of eukaryotic chromatin structure by recursive topological restraints [PDF]
Chromatin structure undergoes many changes during the cell cycle and in response to regulatory events. A basic unit of chromatin organization is the nucleosome core particle.
Dominika Borek, Zbyszek Otwinowski
core +1 more source
Extensive molecular tinkering in the evolution of the membrane attachment mode of the Rheb GTPase [PDF]
Rheb is a conserved and widespread Ras-like GTPase involved in cell growth regulation mediated by the (m)TORC1 kinase complex and implicated in tumourigenesis in humans. Rheb function depends on its association with membranes via prenylated C-terminus, a
Burger, G+15 more
core +2 more sources
Dark Proteome Database: Studies on Disorder [PDF]
There is a misconception that intrinsic disorder in proteins is equivalent to darkness. The present study aims to establish, in the scope of the Swiss-Prot and Dark Proteome databases, the relationship between disorder and darkness.
Agostinho Rosa+4 more
core +1 more source
ABSTRACT Mitochondria of eukaryotic cells are direct descendants of an endosymbiotic bacterium related to Alphaproteobacteria. These organelles retain their own genomes, which are highly reduced and divergent when compared to those of their bacterial relatives.
Ryo Harada+5 more
wiley +1 more source
A common core of secondary structure of the internal transcribed spacer 2 (ITS2) throughout the Eukaryota [PDF]
The ongoing characterization of novel species creates the need for a molecular marker which can be used for species- and, simultaneously, for mega-systematics. Recently, the use of the internal transcribed spacer 2 (ITS2) sequence was suggested, as it shows a high divergence in sequence with an assumed conservation in structure.
Daniel Gerlach+4 more
openaire +3 more sources