Results 141 to 150 of about 618,570 (321)
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
A circuit for secretion-coupled cellular autonomy in multicellular eukaryotic cells. [PDF]
Mol Syst Biol, 2023 Qiao L +11 more
europepmc +1 more source
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]
, 2009 The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core +1 more source
Advanced Healthcare Materials, EarlyView.Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He +4 more
wiley +1 more source
Early "reduction to practice" of the CRISPR-Cas9 invention in eukaryotic cells. [PDF]
Front Genet, 2022 Aquino-Jarquin G.
europepmc +1 more source
Oxidative stress increases eukaryotic initiation factor 4E phosphorylation in vascular cells [PDF]
, 2003 Roger F. Duncan +3 more
openalex +1 more source
Highly efficient 5\u27 capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase [PDF]
, 2018 Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap RNA with the oxidized and reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD+ and NADH, using NAD+ and NADH as non-canonical initiating nucleotides for transcription
Basu, Urmimala +11 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun +11 more
wiley +1 more source
Lungs, Liposomes, Libraries, and Likely Interactions Between Phages and Eukaryotic Cells. [PDF]
Phage (New Rochelle), 2023 Clokie M, Sicheritz-Pontén T.
europepmc +1 more source