Results 171 to 180 of about 618,570 (321)

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

The <i>Shigella flexneri</i> virulence factor apyrase is released inside eukaryotic cells to hijack host cell fate. [PDF]

Microbiol Spectr, 2023
Perruzza L, Zagaglia C, Vitiello L, Sarshar M, Strati F, Pasqua M, Grassi F, Nicoletti M, Palamara AT, Ambrosi C, Scribano D.   +10 more
europepmc   +1 more source

Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells.

, 1982
Stephen H. Leppla
openalex   +2 more sources

Skeletal muscle‐specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21‐mediated non‐cell‐autonomous energy metabolism [PDF]

, 2015
Masato Miyake, Akitoshi Nomura, Atsushi Ogura, Kenji Takehana, Yoshihiro Kitahara, Kazuna Takahara, Kazue Tsugawa, Chinobu Miyamoto, Naoko Miura, Ryosuke Sato, Kiyoe Kurahashi, Heather P. Harding, Miho Oyadomari, David Ron, Seiichi Oyadomari   +14 more
openalex   +1 more source

EUKARYOTIC CELL [PDF]

Eukaryotic Cell, 2009
openaire   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Plasma Membrane Wounding and Repair Assays for Eukaryotic Cells. [PDF]

Bio Protoc, 2022
Sønder SL, Ebstrup ML, Dias C, Heitmann ASB, Nylandsted J.   +4 more
europepmc   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Influence of Lipid Composition of Cationic Liposomes 2X3-DOPE on mRNA Delivery into Eukaryotic Cells. [PDF]

Pharmaceutics, 2022
Vysochinskaya V, Shishlyannikov S, Zabrodskaya Y, Shmendel E, Klotchenko S, Dobrovolskaya O, Dobrovolskaya O, Gavrilova N, Makarova D, Plotnikova M, Elpaeva E, Gorshkov A, Moshkoff D, Maslov M, Vasin A.   +14 more
europepmc   +1 more source

A Stress Response that Allows Highly Mutated Eukaryotic Cells to Survive and Proliferate

, 2022
Rebecca Zabinsky, Jonathan Mares, Richard She, Michelle K. Zeman, Audrey Chang, James D.R. Talbot, E. Campbell, Tina Monzavi, Thomas Silvers, Daniel F. Jarosz   +9 more
openalex   +1 more source