A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang +17 more
wiley +1 more source
Plasma Membrane Wounding and Repair Assays for Eukaryotic Cells. [PDF]
Sønder SL +4 more
europepmc +1 more source
The hyaluronate synthase from a eukaryotic cell line [PDF]
Ludger Klewes, EA Turley, Peter Prehm
openalex +1 more source
Single‐cell transcriptomic profiling of ulcerative colitis (UC) tissues identified downregulation of GFER in intestinal epithelial cells. Mechanistically, GFER interacts with PCBP1 to help maintain intracellular iron homeostasis and may also reduce lipid peroxidation by activating the PGC‐1α/PPARγ signaling pathway, thereby inhibiting ferroptosis ...
Ya Song +5 more
wiley +1 more source
Influence of Lipid Composition of Cationic Liposomes 2X3-DOPE on mRNA Delivery into Eukaryotic Cells. [PDF]
Vysochinskaya V +14 more
europepmc +1 more source
Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells. [PDF]
John F.X. Diffley
openalex +1 more source
GLS1 interacts with RNA polymerase II subunits, ROLR2H and POLR2E, resulting in significant suppression of RNA polymerase II activity. Importantly, the investigation demonstrates that high‐protein diets, particularly glutamine, exert protective effects against alcoholic fatty liver through GLS1‐RNA polymerase II axis.
Wenbiao Wu +17 more
wiley +1 more source
Obstructing Salmonella typhi's virulence in eukaryotic cells through design of its SipB protein antagonists. [PDF]
Ameji JP +3 more
europepmc +1 more source
Translational Control of Programmed Cell Death: Eukaryotic Translation Initiation Factor 4E Blocks Apoptosis in Growth-Factor-Restricted Fibroblasts with Physiologically Expressed or Deregulated Myc [PDF]
Vitaly A. Polunovsky +6 more
openalex +1 more source

