Results 251 to 260 of about 5,903,550 (301)

Automated Bacterial Identification and Morphological Feature Analysis in Low‐Dose Cryo‐EM Using YOLOv11

Advanced Intelligent Discovery, EarlyView.
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula, Lynnicia N. Massenburg, Spenser R. Brown, Amber N. Bible, Chanda R. Harris, Lance X. Zhang, Kiara Parker, Scott T. Retterer, Jennifer L. Morrell‐Falvey, Rama K. Vasudevan, Alexis N. Williams   +10 more
wiley   +1 more source

DeepCPP: A Deep Learning‐Based Framework for Enhanced Prediction of Cell Penetrating Peptides

Advanced Intelligent Systems, EarlyView.
DeepCPP is a multimodal deep learning framework designed to improve the identification of cell‐penetrating peptides. By integrating sequence‐derived evolutionary information with structural graph representations through a dual‐encoder architecture and fusion strategy, the model captures complementary molecular features.
Soualihou Ngnamsie Njimbouom, Candra Zonyfar, Jeong‐Dong Kim   +2 more
wiley   +1 more source

A well‐resolved phylogeny of Cuscuta subgenus Monogynella based on data drawn from all three plant genomes

American Journal of Botany, EarlyView.
Abstract Premise Cuscuta (dodders) consists of ~200 species circumscribed into four subgenera (Monogynella, Cuscuta, Pachystigma, and Grammica) and is the only parasitic genus in Convolvulaceae (the morning‐glory family). This group shows a significant diversity in plastid functionality and represents a rare mixotrophic system among parasitic plants ...
Asawari Albal, Saša Stefanović
wiley   +1 more source

Recurrent Neurodevelopmental Disorder Associated With a Dominant‐Negative TOP2B H63Y Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a 7 year‐old boy with severe neurodevelopmental disorder, medically‐refractory epileptic encephalopathy, hyperkinetic movement disorder, hypotonia, cerebral and cerebellar atrophy and hypomyelination who was found to have a heterozygous de novo TOP2B NM_001330700.2:c.187C>T, p.(His63Tyr) variant.
Zong Yi Ha, Leticia Dinatto, Kirsten Meagher, Colleen Guimond, Jan M. Friedman, Peter C. Stirling, Millan S. Patel   +6 more
wiley   +1 more source

Extending the ATP9A‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this gene was identified as being associated with a recessive neurodevelopmental ...
Camille Verebi, Céline Louveau, Bertrand Diebold, Natacha Gaitch, Arnaud Hubas, Martine Gautier Vallee, Jérôme Champ, Anais L'Haridon, Sophie Georgin Lavialle, Boris Chaumette, Thierry Bienvenu   +10 more
wiley   +1 more source

Synthetic Particulate Subunit Vaccines Co‐Delivering Multiple Antigens Induce Protective Immunity Against Melioidosis

Advanced NanoBiomed Research, EarlyView.
Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir, Shuxiong Chen, Justine B. Bendo, Ashley Johnson, Aleksandra W. Debowski, Mitali Sarkar‐Tyson, Bernd H. A. Rehm   +6 more
wiley   +1 more source

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Phages in eukaryotic cells

Folia Microbiologica, 1985
Urine from a patient after kidney transplantation added to a human embryonic lung culture caused the appearance of dark spots shown to contain cells with phages resembling group A, as well as bodies resembling Chlamydiae.
M, Koukal, I, Trebichavský, J, Horácek, V, Stĕpánová   +3 more
openaire   +2 more sources

The origin of the eukaryotic cell

Trends in Biochemical Sciences, 1996
Molecular sequence data are beginning to provide important insights into the evolutionary origin of eukaryotic cells. Global phylogenies of numerous protein sequences indicate that the eukaryotic cell nucleus is a chimera, which has received major contributions from both a Gram-negative eubacterium and an archaebacterium.
R S, Gupta, G B, Golding
openaire   +2 more sources

Transcriptional Regulation In Eukaryotic Cells

1972
Publisher Summary This chapter provides the theories of transcriptional regulation in eukaryotic cells. Current ideas about the mechanisms involved in differentiation have been very much influenced by the studies on the regulation of protein synthesis both in prokaryotes and eukaryotes.
A J, Macgillivray, J, Paul, G, Threlfall
openaire   +2 more sources

The eukaryotic cell

2003
Abstract Eukaryotes include all organisms that are not bacteria (prokaryotes = eubacteria + archaebacteria). The eukaryotes include the three large groups of multicellular organ isms. That is, animals, (vascular) plants, and the higher fungi plus a large number of rather unrelated groups of unicellular organisms often referred to as ...
openaire   +1 more source