Results 41 to 50 of about 4,853,736 (241)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

The Shelleys and the Idea of Europe [PDF]

open access: yes, 2008
This article explores how the Shelleys and their circle configure ideas of “Europe” between January 1817 and March 1818. I begin with Frankenstein, discussing how Mary Shelley associates Frankenstein's experiment with the particularly “European” problem ...
Stock, Paul
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

The need for ‘Diamond Engagement’ around open access to high quality research output [PDF]

open access: yes
This paper advocates for a co-ordinated cultural shift in their engagement with access to resources in order to make peer-reviewed articles available to a wider audience.
Science Europe
core  

Les “sept” Europe [PDF]

open access: yesPopulation & Avenir, 2009
It is often said that Europe is the most ill-defined of continents. As a result, the size of the European population and its relative weight in the world vary according to the geographic area selected. Seven such areas can be identified.
openaire   +4 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Welcome to Europe [PDF]

open access: yes
Bruegel Fellow Jakob von Weizsäcker argues that Europe needs more high-skilled migration and the debate on low-skilled migration should not be an excuse to slow this process down.
Jakob von Weizsäcker
core   +1 more source

Chalk cliff retreat in East Sussex and Kent 1870s to 2001 [PDF]

open access: yes, 2006
The retreat of chalk cliffs fringing the eastern English Channel contributes shingle to the beaches which helps to protect the cliffs and slow down erosion. Conversely, cliff retreat endangers settlements and infrastructure on the clifftop.
Anders F. J.   +13 more
core   +2 more sources

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Whither growth in central and eastern Europe? Policy lessons for an integrated Europe [PDF]

open access: yes
In this Blueprint, Bruegel Resident Fellows Zsolt Darvas, Jean Pisani-Ferry, André Sapir and their co-authors Torbjörn Becker, Daniel Daianu, Vladimir Gligorov, Michael A Landesmann, Pavle Petrovic, Dariusz K.
André Sapir   +8 more
core   +1 more source

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