Results 51 to 60 of about 129,071 (299)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Relative incompetence of European rabbits for Lyme disease spirochaetes [PDF]
Parasitology, 2000 To determine whether rabbits may serve as reservoir hosts for Lyme disease spirochaetes in Europe, we compared their competence as hosts for Borrelia afzelii, one of the most prevalent European spirochaetal variants, with that of the Mongolian jird.
Matuschka, F.-R. +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Abstracts of the 46th Symposium on Cuniculture, ASESCU
World Rabbit Science, 2022 The 46th Congress of the Spanish Association of Cuniculture (ASESCU) was held in Pineda de Mar (Barcelona, Catalonia, Spain) from 1st to 2nd June 2022, hosted by the Institute of Agrifood Research and Technology (IRTA) and the Department of Climate ...
Abstracts, Conferences, Congresses, Symposiums...
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 1997 [EN] The purpose of this paper is to review sorne new results about genetics of the rabbit for meat production. We examine 4 key issues : (i) domestication of the rabbit took place few hundred years ago; European Community has just approved a program ...
de Rochambeau, H., ROCHAMBEAU, H. de
core +1 more source
Ecosphere, 2015 Reforestation has been widely adopted as a solution to multiple global change issues. However, the role of herbivory by invasive species in the restoration of grassland to forest has received little attention.
David M. Forsyth +7 more
doaj +1 more source
A Potential Atypical Case of Rabbit Haemorrhagic Disease in a Dwarf Rabbit
Animals, 2020 Rabbit haemorrhagic disease (RHD) is a highly contagious infectious disease of European wild and domestic rabbits. Rabbit haemorrhagic disease virus (RHDV, GI.1) emerged in 1986 in Europe, rapidly spreading all over the world.
Fábio A. Abade dos Santos +5 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
BIOSTIMULATIONS APPLIED TO RABBIT REPRODUCTION: THEORY AND PRACTICE
, 1998 [EN] Rabbit artificial insemination is now commonly practised in European countrles. In arder to maintain a "natural image" of rabbit meat and to be consistent with animal welfare, authors discuss the interest of biostimulation methods defined in ...
Theau- Clément, M. +3 more
core +1 more source