Results 91 to 100 of about 9,251,887 (309)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The Issue of Sovereignty in an Ever-Closer Union
Croatian Yearbook of European Law and Policy, 2014 This paper aims to answer the following question: what is the understanding of the principle of sovereignty in the EU today, and how should this knowledge inform our actions tomorrow?
Tina Oršolić Dalessio
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
"The Unbearable Lightness of Complying with European Immigration Policies? Germany’s First Mover Advantage" [PDF]
, 2007 The last decade has seen an increasing interest on the domestic repercussions of the European Union polity, politics and policies on its member states. Despite the fact that Justice and Home Affairs in general and immigration policies in particular have ...
Ette, Andreas., Kreienbrink, Axel.
core
The European Commission: Space and the Arctic [PDF]
, 2012 Accompanying the document: Joint communication: Developing a European Union Policy towards the Arctic Region: progress since 2008 and next steps (http://library.arcticportal.org/1698/).
European Commission, -
core +1 more source
Quality of Life Indicators in Selected European Countries: Hierarchical Cluster Analysis Approach
Croatian Review of Economic, Business and Social Statistics, 2015 The average expected duration of human life is rising because of different reasons. On the other hand, not only the duration, but the quality of life level is important, too.
Žmuk Berislav
doaj +1 more source
The rise of the European consolidation state [PDF]
, 2015 The rise of the consolidation state follows the displacement of the classical tax state, or Steuerstaat, by what I have called the debt state, a process that began in the 1980s in all rich capitalist democracies. Consolidation is the contemporary response to the “fiscal crisis of the state” envisaged as early as the late 1960s, when postwar growth had ...
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
"The timing of EU membership and its effect on national legislative oversight of European affairs" [PDF]
, 2007 This paper explores the effects of European integration on national level legislatures in European Union member states. Many economic and political decisions previously made by democratically elected national legislatures are now decided at a ...
Hamerly, Ivy.
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source