Results 121 to 130 of about 5,386,899 (294)

Fc‐Dependent Targeting of the GAS6–MERTK Axis With Monoclonal and Bispecific Antibodies Overcomes Drug Resistance Across EGFR Mutations in Exons 19, 20, and 21

Advanced Science, EarlyView.
EGFR mutations drive a substantial fraction of non‐small cell lung cancers (NSCLC) and are effectively targeted by tyrosine kinase inhibitors (TKIs), including osimertinib. However, resistance inevitably develops through secondary mutations and compensatory receptor activation, including the GAS6 receptor MERTK.
Suvendu Giri, Boobash Raj Selvadurai, Nitin Gupta, Arturo Simoni‐Nieves, Alessandro Genna, Moshit Lindzen, Rishita Chatterjee, Marieke Van Daele, Deepthi Ramesh Kumar, Mirie Zerbib, Roni Oren, Isabelle Sophie Meijer, Elisabeth Franziska Wippich, Yahel Avraham, Rony Dahan, Yuya Haga, Laura E. Kilpatrick, Simon Platt, Stephen J. Hill, Lipika R. Pal, Eytan Ruppin, Yasuo Tsutsumi, Eliane Hadas Yardeni, Muhammad Abu Ahmad, Olga Radinsky, Donatella Romaniello, Mattia Lauriola, Angel Porgador, Yosef Yarden   +28 more
wiley   +1 more source

Abstracts of the Genetics Section presented during the 8th World Rabbit Congress. Puebla, Mexico 7-10, 2004 [PDF]

, 2005
World Rabbit Science (2005). Abstracts of the Genetics Section presented during the 8th World Rabbit Congress. Puebla, Mexico 7-10, 2004. World Rabbit Science. 13(1):49-64.
World Rabbit Science, Abstracts, Conferences, Congresses, Symposiums...   +1 more
core   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

Abstracts of the communications presented during the 13th Hungarian Conference on Rabbit Production, Kaposvár (Hungary). May 23, 2001 [PDF]

, 2002
World Rabbit Science (2002). Abstracts of the communications presented during the 13th Hungarian Conference on Rabbit Production, Kaposvár (Hungary). May 23, 2001. World Rabbit Science. 10(1).
World Rabbit Science, Abstracts, Conferences, Congresses, Symposiums...   +1 more
core   +1 more source

Lagomorph cranial biomechanics and the functional significance of the unique fenestrated rostrum of leporids

The Anatomical Record, EarlyView.
Abstract The crania of leporid lagomorphs are uniquely fenestrated, including the posterior cranial bones and the lateral portion of the maxilla. The functional significance of the highly fenestrated rostrum has received considerably little attention, despite being absent in other mammalian herbivores with a long rostrum.
Amber P. Wood‐Bailey, Alana C. Sharp
wiley   +1 more source

Abstracts of the Feeding and Nutrition section presented during the "8th World Rabbit Congress", Puebla, México 7-10, 2004 [PDF]

, 2006
World Rabbit Science (2006). Abstracts of the Feeding and Nutrition section presented during the "8th World Rabbit Congress", Puebla, México 7-10, 2004. World Rabbit Science. 14(1).
World Rabbit Science, Abstracts, Conferences, Congresses, Symposiums...   +1 more
core   +1 more source

Evolutionary history and molecular epidemiology of rabbit haemorrhagic disease virus in the Iberian Peninsula and Western Europe

BMC Evolutionary Biology, 2010
Background Rabbit haemorrhagic disease virus (RHDV) is a highly virulent calicivirus, first described in domestic rabbits in China in 1984. RHDV appears to be a mutant form of a benign virus that existed in Europe long before the first outbreak.
Rocha Gregorio, Merchán Tomás, Suárez Mónica, Gaitero Tania, Alda Fernando, Doadrio Ignacio   +5 more
doaj   +1 more source

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

The Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen, Emma Sherratt, Philip Stott, Rachel Norris   +3 more
wiley   +1 more source

Abstracts of the papers presented during the 3rd scientific conference of rabbit production in hot climates, Hurghada, Egypt. 8 - 11 October 2002 [PDF]

, 2004
World Rabbit Science (2004). Abstracts of the papers presented during the 3rd scientific conference of rabbit production in hot climates, Hurghada, Egypt. 8 - 11 October 2002. World Rabbit Science. 12(3):185-222.
Hurghada, Egypt. 8 - 11 October 2002.,, World Rabbit Science   +1 more
core   +1 more source

Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization

Scientific Reports
Lagoviruses are viruses of the Caliciviridae family affecting lagomorphs. Both pathogenic and non-pathogenic lagoviruses affect the European rabbit (Oryctolagus cuniculus), and they are phylogenetically distinguished.
Patrizia Cavadini, Alice Vismarra, Francesca Merzoni, Vittoria Di Giovanni, Maria Beatrice Boniotti, Lorenzo Capucci, Antonio Lavazza   +6 more
doaj   +1 more source