The FOXQ1/SSBP2 Regulatory Axis Drives Malignant Progression of Melanoma
ABSTRACT Melanoma is a highly aggressive skin cancer with poor prognosis, often linked to excessive UV exposure. Despite advancements in immunotherapy and targeted treatments, melanoma's invasiveness and metastatic potential remain significant challenges.
Xiaoyu Zhang +4 more
wiley +1 more source
Experimental Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Alpacas, 2026. [PDF]
Schön J +7 more
europepmc +1 more source
Hepatic B‐cell lymphoma in a wild European badger (Meles meles) in the UK
Abstract Neoplastic diseases are considered rare in wild European badgers (Meles meles) with a single pelioid hepatocellular carcinoma, and four lymphoma cases (two T‐cell, two unclassified) in the literature. A found‐dead, elderly, male wild badger underwent postmortem examination for Mycobacterium bovis surveillance.
Shauna Anne Hilton +3 more
wiley +1 more source
Chimeric SARS-CoV-2 vaccine vectors stably incorporating the functional glycoprotein of VSV. [PDF]
Kipfer ET +7 more
europepmc +1 more source
In Vivo Partial Cell Reprogramming With Yamanaka Factors Reduced Ischemic Brain Damage in Aging Mice
Short‐term cyclic partial reprogramming with Yamanaka factors protects aged mice from ischemic brain injury, preserving cognitive function, myelin integrity, and neuronal density, supporting partial reprogramming as a promising neuroprotective intervention in aging.
Paula R. Mallavibarrena +5 more
wiley +1 more source
Haemodynamic control of zonated liver function via instructive vascular Wnt signalling. [PDF]
Lee KH +28 more
europepmc +1 more source
A Novel Peptide Targeting the USP25–SIRT1 Interaction Activates SIRT1 to Suppress Cell Senescence
USP25‐mediated K63‐linked deubiquitination of SIRT1 at K506 and K513 suppresses its activity to promote senescence. These findings unveil a novel aging regulatory axis and identify a peptide targeting the USP25–SIRT1 interaction for anti‐senescence therapeutic intervention.
YuJuan Zhou +14 more
wiley +1 more source
Enrichment and Reduction of Microsatellite Regions in the Myxoma Virus Genome Following Species Jump to the Iberian Hare (<i>Lepus granatensis</i>). [PDF]
Menéndez-Manjón A +20 more
europepmc +1 more source
ABSTRACT Introduction Toscana virus (TOSV) and Leishmania species are sand fly‐borne pathogens that pose a significant public health threat and an increasing risk of exposure in Europe. The objective of this study was to identify the phleboviruses circulating in an area endemic for sand fly‐borne pathogens and to estimate infection prevalence in wild ...
Andrés Torres‐Llamas +8 more
wiley +1 more source
Widespread presence of novel gammaherpesviruses in lagomorph species (Oryctolagus cuniculus, Lepus spp. and Ochotona alpina). [PDF]
Matos MC, Abrantes J, Lopes AM.
europepmc +1 more source

