Results 111 to 120 of about 35,900 (294)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
How European Protest Transforms Institutions of the Public Sphere - Discourse and Decision-Making in the European Social Forum Process [PDF]
Against the background of the alleged democratic deficit of EU institutions, this case study explores how politicization and emerging transnational public spaces in European protest movements innovate existing practices of discursive or grassroots ...
Nicole Doerr
core
The limits of conditionality and Europeanization: Turkey’s dilemmas in adopting the EU acquis on asylum [PDF]
, 2007 [From the introduction]. The purpose of this paper is to explore the impact of “uncertainty over ultimate membership” on Schimmelfening and Sedelmeier model of conditionality as a factor that explains Europeanization.
Kirisci, Kemal.
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
EU-Ukraine "deep" trade agenda: the effectiveness and impact perspectives. [PDF]
Int Polit (Hague), 2022 Rabinovych M.
europepmc +1 more source
'Let's talk about Europe'. Explaining vertical and horizontal Europeanization in the quality press [PDF]
, 2007 This paper contributes to the ongoing quest for a European public sphere understood as a structural transformation of national media debates. The process of Europeanization has a vertical and a horizontal dimension: an increased focus on the EU as well ...
Brüggemann, Michael +1 more
core
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
¿Hacia la europeización de los Parlamentos autonómicos? Reflexiones al hilo del mecanismo de alerta temprana [PDF]
Revista d'Estudis Autonòmics i Federals, 2012 Traditionally, the regional parliaments have been excluded from European decision-making and have occupied an invisible place in that context. The early warning system in monitoring the principle of subsidiariety introduced by the Treaty of Lisbon ...
Ana M. Carmona Contreras
doaj