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Quassinoids from Eurycoma longifolia

Phytochemistry, 2002
Three quassinoids, eurycolactone D (1), eurycolactone E (2) and eurycolactone F (3) were isolated from the roots of Eurycoma longifolia Jack. The structures of 1-3 were elucidated by spectroscopic methods, and that of 3 was further confirmed by X-ray crystallography.
Hooi Hoon, Ang   +3 more
openaire   +3 more sources

Cytotoxic and Antimalarial Constituents of the Roots of Eurycoma longifolia

Journal of Natural Products, 1991
By bioactivity-directed fractionation, five cytotoxic constituents have been characterized from the roots of Eurycoma longifolia collected in Kalimantan, Indonesia. Four canthin-6-one alkaloids, namely, 9-methoxycanthin-6-one, 9-methoxycanthin-6-one-N-oxide, 9-hydroxycanthin-6-one, and 9-hydroxycanthin-6-one-N-oxide, and one quassinoid, eurycomanone ...
L B, Kardono   +5 more
openaire   +4 more sources

Quassinoids from Eurycoma harmandiana

Phytochemistry, 2001
Three quassinoids, iandonosides A and B and iandonone, were isolated from the root of Eurycoma harmandiana, along with five known quassinoids, casteloside B, 13 beta, 21-dihydroeurycomanone, chaparrinone, glaucarubolone and ailanquassin B as well as the coumarin, scopoletin. The structural elucidations were based on analyses of spectroscopic data.
T, Kanchanapoom   +3 more
openaire   +2 more sources

Quassinoids from Eurycoma longifolia

Journal of Natural Products, 2009
Ten new structurally diverse quassinoids (1-10) and 14 known compounds were isolated from the stems of Eurycoma longifolia. The new compounds were two eurycomanone-type C(20) quassinoids (1, 2), one klaineanone-type C(20) quassinoid (3), one C(19) quassinoid (4) with a 1,2-seco-1-nor-6(5-->10)-abeo-picrasan-2,5-olide skeleton, and six eurycomalactone ...
Katsunori, Miyake   +4 more
openaire   +2 more sources

The Toxicity of Some Quassinoids from Eurycoma longifolia

Planta Medica, 2002
The 50 % aqueous ethanol extract of Eurycoma longifolia Jack (Simaroubaceace) roots was partitioned with diethyl ether, n-butanol and then water. Acute toxicity studies of each fraction on mice administered orally and brine shrimps revealed that the n-butanol fraction was the most toxic.
Kit-Lam, Chan, Chee-Yan, Choo
openaire   +2 more sources

Antiinflammatory and analgesic effects of Eurycoma longifolia extracts

Archives of Pharmacal Research, 2016
Eurycoma longifolia is one of the most popular herbal medicines in Southeast Asia. The purpose of this study is to evaluate the analgesic and anti-inflammatory effects of the methanolic extract of E. longifolia roots (TA) in vivo and to investigate the underlying mechanisms.
Young Min, Han   +6 more
openaire   +2 more sources

Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia

Bioorganic & Medicinal Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Ping-Chung, Kuo   +3 more
openaire   +2 more sources

Quassinoids from Eurycoma longifolia with antiviral activities by inhibiting dengue virus replication.

Phytomedicine, 2023
BACKGROUND Dengue caused by dengue virus (DENV) spreads rapidly around the world. However, there are no worldwide licensed vaccines or specific antivirals to combat DENV infection. Quassinoids are the most characteristic components of Eurycoma longifolia,
Xuemei He   +9 more
semanticscholar   +1 more source

Squalene derivatives from Eurycoma longifolia

Phytochemistry, 1993
Abstract Three novel cytotoxic squalene-type triterpenes, eurylene, 14-deacetyl eurylene and longilene peroxide, together with teurilene were isolated from ...
Hiroshi Morita   +4 more
openaire   +1 more source

Biphenylneolignans from wood of Eurycoma longifolia

Phytochemistry, 1992
Abstract Two novel isomeric 2,2′-dimethoxy-4-(3-hydroxy-1-propenyl)-4′-(1,2,3-trihydroxypropyl) diphenyl ethers, and two novel biphenyls, 2-hydroxy-3,2′,6′-trimethoxy-4′-(2,3-epoxy-1-hydroxypropyl)-5-(3-hydroxy-1-propenyl)-biphenyl and 2-hydroxy-3,2′-dimethoxy-4′-(2,3-epoxy-1-hydroxypropyl)-5-(3-hydroxy-1-propenyl)-biphenyl, were isolated from the ...
Hiroshi Morita   +3 more
openaire   +1 more source

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