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Quassinoids from Eurycoma longifolia
Phytochemistry, 2002Three quassinoids, eurycolactone D (1), eurycolactone E (2) and eurycolactone F (3) were isolated from the roots of Eurycoma longifolia Jack. The structures of 1-3 were elucidated by spectroscopic methods, and that of 3 was further confirmed by X-ray crystallography.
Hooi Hoon, Ang +3 more
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Cytotoxic and Antimalarial Constituents of the Roots of Eurycoma longifolia
Journal of Natural Products, 1991By bioactivity-directed fractionation, five cytotoxic constituents have been characterized from the roots of Eurycoma longifolia collected in Kalimantan, Indonesia. Four canthin-6-one alkaloids, namely, 9-methoxycanthin-6-one, 9-methoxycanthin-6-one-N-oxide, 9-hydroxycanthin-6-one, and 9-hydroxycanthin-6-one-N-oxide, and one quassinoid, eurycomanone ...
L B, Kardono +5 more
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Quassinoids from Eurycoma harmandiana
Phytochemistry, 2001Three quassinoids, iandonosides A and B and iandonone, were isolated from the root of Eurycoma harmandiana, along with five known quassinoids, casteloside B, 13 beta, 21-dihydroeurycomanone, chaparrinone, glaucarubolone and ailanquassin B as well as the coumarin, scopoletin. The structural elucidations were based on analyses of spectroscopic data.
T, Kanchanapoom +3 more
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Quassinoids from Eurycoma longifolia
Journal of Natural Products, 2009Ten new structurally diverse quassinoids (1-10) and 14 known compounds were isolated from the stems of Eurycoma longifolia. The new compounds were two eurycomanone-type C(20) quassinoids (1, 2), one klaineanone-type C(20) quassinoid (3), one C(19) quassinoid (4) with a 1,2-seco-1-nor-6(5-->10)-abeo-picrasan-2,5-olide skeleton, and six eurycomalactone ...
Katsunori, Miyake +4 more
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The Toxicity of Some Quassinoids from Eurycoma longifolia
Planta Medica, 2002The 50 % aqueous ethanol extract of Eurycoma longifolia Jack (Simaroubaceace) roots was partitioned with diethyl ether, n-butanol and then water. Acute toxicity studies of each fraction on mice administered orally and brine shrimps revealed that the n-butanol fraction was the most toxic.
Kit-Lam, Chan, Chee-Yan, Choo
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Antiinflammatory and analgesic effects of Eurycoma longifolia extracts
Archives of Pharmacal Research, 2016Eurycoma longifolia is one of the most popular herbal medicines in Southeast Asia. The purpose of this study is to evaluate the analgesic and anti-inflammatory effects of the methanolic extract of E. longifolia roots (TA) in vivo and to investigate the underlying mechanisms.
Young Min, Han +6 more
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Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia
Bioorganic & Medicinal Chemistry, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Ping-Chung, Kuo +3 more
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Phytomedicine, 2023
BACKGROUND Dengue caused by dengue virus (DENV) spreads rapidly around the world. However, there are no worldwide licensed vaccines or specific antivirals to combat DENV infection. Quassinoids are the most characteristic components of Eurycoma longifolia,
Xuemei He +9 more
semanticscholar +1 more source
BACKGROUND Dengue caused by dengue virus (DENV) spreads rapidly around the world. However, there are no worldwide licensed vaccines or specific antivirals to combat DENV infection. Quassinoids are the most characteristic components of Eurycoma longifolia,
Xuemei He +9 more
semanticscholar +1 more source
Squalene derivatives from Eurycoma longifolia
Phytochemistry, 1993Abstract Three novel cytotoxic squalene-type triterpenes, eurylene, 14-deacetyl eurylene and longilene peroxide, together with teurilene were isolated from ...
Hiroshi Morita +4 more
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Biphenylneolignans from wood of Eurycoma longifolia
Phytochemistry, 1992Abstract Two novel isomeric 2,2′-dimethoxy-4-(3-hydroxy-1-propenyl)-4′-(1,2,3-trihydroxypropyl) diphenyl ethers, and two novel biphenyls, 2-hydroxy-3,2′,6′-trimethoxy-4′-(2,3-epoxy-1-hydroxypropyl)-5-(3-hydroxy-1-propenyl)-biphenyl and 2-hydroxy-3,2′-dimethoxy-4′-(2,3-epoxy-1-hydroxypropyl)-5-(3-hydroxy-1-propenyl)-biphenyl, were isolated from the ...
Hiroshi Morita +3 more
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