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The Possible Benefits of Tongkat Ali (Eurycoma longifolia) Extract for the Treatment of Cancer

Middle East Research Journal of Biological Sciences
Background: In recent years, phytochemicals have gained international scientific recognition for their potential to prevent major health problems. Research on the chemical structures and pharmacological mechanisms of plant extracts with anticancer ...
M. Madhloom
semanticscholar   +1 more source

Eurycomalin A, a New Dimeric Dihydrobenzofuran from Eurycoma longifolia

HETEROCYCLES, 2004
One new dimeric 2-isopropenyl-2, 3-dihydrobenzofuran, eurycomalin A (1), was characterized from the methanol extract of the root of Eurycoma longifolia by the 1D and 2D spectral and chemical transformation studies. The reported structure of eurycomalide A (2) was revised through detail 2D spectral analyses.
Ping‐Chung Kuo   +3 more
openaire   +1 more source

Quassinoids from Eurycoma longifolia as plant growth inhibitors

Phytochemistry, 2001
Seven quassinoids including a new 12-epi-11-dehydroklaineanone were isolated from the leaves of Eurycoma longifolia (Simaroubaceae) as plant growth inhibitors or related compounds. The strongest activity was found in 14,15beta-dihydroxyklaineanone.
S, Jiwajinda   +4 more
openaire   +2 more sources

New antiulcer quassinoids from Eurycoma longifolia

European Journal of Medicinal Chemistry, 1991
Abstract A bioassay study of Pasak bumi (Eurycoma longifolia) led to the isolation of four quassinoids, pasakbumin-A (1), -B (2), -C (4), and -D (7). Both pasakbumin-A (= eurycomanone) 1 and pasakbumin-B 2 exhibited potent antiulcer activity. This prompted us to test some modified quassinoids to reveal that ailanthone (8), the main quassinoid of ...
H Tada   +5 more
openaire   +1 more source

Quassinoids from Eurycoma longifolia as Potential Dihydrofolate Reductase Inhibitors: A Computational Study.

Current Pharmaceutical Biotechnology
BACKGROUND Quassinoids are degraded triterpene compounds that can be obtained from various species of the Simaroubaceae plant family, including Eurycoma longifolia. Quassinoids are the major compounds in E.
N. Yunos   +3 more
semanticscholar   +1 more source

In Vitro Shoot Organogenesis of Eurycoma longifolia

The Planter, 2002
Direct shoot organogenesis could be induced from the shoots, nodes and cotyledon tissues of the in vitro Eurycoma longifolia seedlings. Multiple shoots could be formed from shoot and node explants that were cultured in MS medium + 1.50 mg/L BAP + 0.25 mg/L NAA. While cotyledon tissues could produce multiple shoots when cultured in MS medium + 0.75 mg/L
openaire   +1 more source

PLS-based integration of metabolomics and transcriptomics to reveal the effect of different growth years on Eurycoma longifolia roots and hairy root cultures

Plant Biosystems
Growth years are important factors that affect the accumulation of secondary metabolites in Eurycoma longifolia roots. This study aimed to investigate the effect of different growth years on the metabolites and gene expression of E.
Nur Nabilah Alias   +2 more
semanticscholar   +1 more source

6α-Hydroxyeurycomalactone, a quassinoid from Eurycoma longifolia

Phytochemistry, 1992
Abstract The structure of 6α-hydroxyeurycomalactone, a new C19 quassinoid, isolated from the roots of Eurycoma longifolia has been established from spectral and by single crystal X-ray analysis; eurycomalactone was also isolated. The cytotoxic activity of some quassinoids from this plant is not mediated through DNA cleaving properties.
K.L. Chan   +5 more
openaire   +1 more source

Highly oxygenated quassinoids from Eurycoma longifolia

Phytochemistry, 1993
Abstract Two novel C 19 -skeleton quassinoids, one with a lactonic linkage at C-7 and another with a lactonic linkage at C-12, and seven novel highly oxygenated quassinoids with a C 20 -skeleton were isolated from the leaves of Eurycoma longifolia .
Hiroshi Morita   +4 more
openaire   +1 more source

Effect of Allium sativum, Thunbergia laurifolia, and Eurycoma longifolia crude extracts on the minute intestinal fluke, Haplorchis taichui.

Tropical biomedicine
Haplorchis taichui is the minute intestinal fluke (MIF), presents a significant public health concern in Thailand. Despite praziquantel (PZQ) being the main treatment, concerns over recurrent use and drug resistance have surfaced.
P. Pechdee   +8 more
semanticscholar   +1 more source

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