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Enterovirus D68 receptor usage: from static attachment to dynamic entry. [PDF]

J Virol
Liu D, Ji Z, Zheng X, Xia H, Yang W, Ge P-F, Wei W.   +6 more
europepmc   +1 more source

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Neuroinvasive EV-D68 infection in cerebral organoids mimics human pathology

The Journal of Immunology, 2023
Abstract Emerging viruses with the capacity to cause neurological disease remain a global health threat. One such virus, Enterovirus-D68 (EV-D68), has recently received attention due to an associative rise in cases of a polio-like paralytic disease called acute flaccid myelitis (AFM) in some children.
Christine Vazquez, Beatrice Han, Carl Bannerman, Seble G Negatu, Angelina Bongiovanni, Emma Lanoce, Guo-Li Ming, Kellie Ann Jurado   +7 more
openaire   +1 more source

Seroepidemiology of enterovirus D68 infection in China

Emerging Microbes and Infections, 2017
Human enterovirus 68 (EV-D68) is a rarely reported virus that has been linked to respiratory disease. In recent years, reports about EV-D68 infection have markedly increased worldwide.
Zichun Xiang, Taisheng Li, Glaucia Paranhos-Baccala   +2 more
exaly   +2 more sources

EV-D68 steps up its neurotropism

Nature Reviews Microbiology, 2018
Recently emerged enteroviruses have been linked to acute paralysis, and a new study now shows that these viruses have developed neurotropism.
openaire   +2 more sources

Targeting EV-D68, a respiratory virus

Science, 2015
Virus Structure A recent outbreak of respiratory illness in U.S. children was caused by entorovirus D68 (EV-D68). Enteroviruses also include human pathogens such as human rhinovirus, which causes the common cold, and poliovirus.
openaire   +1 more source

Prevalence and clinical presentation of EV-D68 infections in Kansas City children during the 2022 season

Diagnostic Microbiology and Infectious Disease, 2023
Seasonal EV-D68 infections can strain medical care resources due to increased pediatric hospitalizations for respiratory illness. In this study, we examine Kansas City's 2022 EV-D68 season. Rhinovirus/enterovirus (RV/EV) positive respiratory specimens from standard of care testing were salvaged and tested by EV-D68 specific PCR. Of the 1412 respiratory
Stephanie Gummersheimer, Amanda Hayes, Christopher Harrison, Brian Lee, Jennifer Schuster, Minati Dhar, Anjana Sasidharan, Dithi Banerjee, Rangaraj Selvarangan   +8 more
openaire   +2 more sources

Current Understanding of Human Enterovirus D68

Viruses, 2019
Human enterovirus D68 (EV-D68), a member of the species Enterovirus D of the Picornaviridae family, was first isolated in 1962 in the United States. EV-D68 infection was only infrequently reported until an outbreak occurred in 2014 in the US; since then,
Jing Sun, Xiao-Fang Yu, Sun Jing
exaly   +2 more sources

Regulation of the proteostasis network during enterovirus infection: A feedforward mechanism for EV-A71 and EV-D68

Antiviral Research, 2021
The proteostasis network guarantees successful protein synthesis, folding, transportation, and degradation. Mounting evidence has revealed that this network maintains proteome integrity and is linked to cellular physiology, pathology, and virus infection. Human enterovirus A71 (EV-A71) and EV-D68 are suspected causative agents of acute flaccid myelitis,
Jia-Rong Jheng, Yuan-Siao Chen, Jim-Tong Horng   +2 more
openaire   +2 more sources