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Targeting EV-D68, a respiratory virus
Science, 2015Virus Structure A recent outbreak of respiratory illness in U.S. children was caused by entorovirus D68 (EV-D68). Enteroviruses also include human pathogens such as human rhinovirus, which causes the common cold, and poliovirus.
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Antiviral Research, 2021
The proteostasis network guarantees successful protein synthesis, folding, transportation, and degradation. Mounting evidence has revealed that this network maintains proteome integrity and is linked to cellular physiology, pathology, and virus infection. Human enterovirus A71 (EV-A71) and EV-D68 are suspected causative agents of acute flaccid myelitis,
Jia-Rong Jheng +2 more
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The proteostasis network guarantees successful protein synthesis, folding, transportation, and degradation. Mounting evidence has revealed that this network maintains proteome integrity and is linked to cellular physiology, pathology, and virus infection. Human enterovirus A71 (EV-A71) and EV-D68 are suspected causative agents of acute flaccid myelitis,
Jia-Rong Jheng +2 more
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Epidemiological and clinical review on the current knowledge of EV-D68
International Journal of Biological and Pharmaceutical Sciences ArchiveЕnterovirus D68 (EV-D68) is a unique non-polio enterovirus, first identified in 1962. The wide spread of the virus in recent years has posed a threat to public health. EV-D68 typically causes respiratory illness, which can be mild (like a common cold) or more severe. The studies have demonstrated the potential for EV-D68 to induce neurological disease.
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[Expression and Preliminary Research on the Soluble Domain of EV-D68 3A Protein].
Bing du xue bao = Chinese journal of virology, 2016To understand the structure of the soluble region of Enterovirus 68 3A protein, we construct a prokaryotic expression vector expressing the soluble region of EV-D68 3A protein, and identify the forms of expression product after purification. The EV-D68 3A(1-61) gene was amplified by PCR and then cloned into the expression vector pET-28a-His-SUMO.
Ting, Li +3 more
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Pediatric Pulmonology
Abstract Background Human enterovirus D68 (EV‐D68) has been associated with an increase in mild‐to‐severe pediatric respiratory diseases in western countries. However, the prevalence and clinical characteristics of EV‐D68‐associated pneumonia in China remain understudied.
Shasha Xu +7 more
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Abstract Background Human enterovirus D68 (EV‐D68) has been associated with an increase in mild‐to‐severe pediatric respiratory diseases in western countries. However, the prevalence and clinical characteristics of EV‐D68‐associated pneumonia in China remain understudied.
Shasha Xu +7 more
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Starvation after infection restricts enterovirus D68 replication.
Autophagy, 2023Ganna Galitska +2 more
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Development of Novel PCR Assays for Improved Detection of Enterovirus D68.
Journal of Clinical Microbiology, 2021Tatsuki Ikuse +2 more
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Enterovirus D68 Antivirals: Past, Present, and Future
ACS Infectious Diseases, 2020Jun Wang, Yanmei Hu, Rami Musharrafieh
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ICAM-5/Telencephalin Is a Functional Entry Receptor for Enterovirus D68
Cell Host and Microbe, 2016Shu Zheng, Wei Wei, Xiao-Fang Yu
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Enterovirus D68 receptor requirements unveiled by haploid genetics
Proceedings of the National Academy of Sciences of the United States of America, 2016Hendrik Jan Thibaut +2 more
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