Results 51 to 60 of about 145,096 (291)
Applying the lessons of the attack on the World Trade Center, 11th September 2001, to the design and use of interactive evacuation simulations [PDF]
, 2005 The collapse of buildings, such as terminal 2E at Paris' Charles de Gaule Airport, and of fires, such as the Rhode Island, Station Night Club tragedy, has focused public attention on the safety of large public buildings.
C. W. Johnson, Johnson, C.W.
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
ПРОРЫВ (новые грани истории Великой Отечественной Войны в Калмыкии)
Oriental Studies, 2018 In this article analyzed the historiography on the history of Kalmykia during wartime, including K.N.Maksimov's monography «The Great Patriotic War: Kalmykia and the Kalmyks» (М.: Nauka 2007).
Yuli Ochirovich Oglaev
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Evacuation of Persons from Selected Departments in High-Rise Buildings of Healthcare Facilities
Communications, 2016 The article deals with the evacuation of persons from hospital bed wards in high-rise buildings of medical facilities. It presents a proposal for a systems approach and provides a subsequent supportive methodology and tools for planning and ...
Silvie Benesova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Guidelines for assessing pedestrian evacuation software applications [PDF]
, 2007 This paper serves to clearly identify and explain criteria to consider when evaluating the suitability of a pedestrian evacuation software application to assess the evacuation process of a building.
Castle, C.J.E., Castle, CJE
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The Analysis of Tsunami Vertical Shelter in Padang City [PDF]
, 2014 Padang is a coastal city, which is located opposite to the Indian Ocean. Just across Padang city there are areas of subduction, which can trigger a powerful earthquake and generate tsunami.
Amaratunga, Dilanthi +2 more
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Deceleration in The Micro Traffic Model and Its Application to Simulation for Evacuation from Disaster Area [PDF]
, 2011 Referring to the Nagel–Schreckenberg’s (NaSch) model, we have studied the impact of agent and diligent driver into the micro traffic model in the case of evacuation. This study is attention to the deceleration that added in the micro traffic model.
Kohei, Arai, Tri, Harsono
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