Results 71 to 80 of about 423,821 (335)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Telemedical Technologies at the Pre-Hospital Stage: Practice of Application
Неотложная медицинская помощьTelemedicine technologies for transmitting digital information about the patient are presented and characterized in the practice of application at the prehospital stage for clarifying the diagnosis, correcting the measures taken, efficient logistics and ...
R. E. Filyavin +3 more
doaj +1 more source
Управленческое консультирование, 2020 The Features of state management of secondary schools during the great Patriotic war were determined by the focus on solving two major problems: the preservation of the school system and its reconstruction in accordance with the requirements of wartime ...
N. K. Gurkina
doaj +1 more source
Capacity Based Evacuation with Dynamic Exit Signs
, 2013 Exit paths in buildings are designed to minimise evacuation time when the building is at full capacity. We present an evacuation support system which does this regardless of the number of evacuees.
Desmet, Antoine, Gelenbe, Erol
core +1 more source
Statistical fluctuations in pedestrian evacuation times and the effect of social contagion [PDF]
, 2016 Mathematical models of pedestrian evacuation and the associated simulation software have become essential tools for the assessment of the safety of public facilities and buildings.
Bouzat, Sebastián +2 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Multi-Period Evacuation Shelter Selection considering Dynamic Hazards Assessment
Indonesian Journal of Computing, Engineering and Design, 2019 Natural phenomena may lead to a huge disaster that is affected by triggering phenomenon and the following phenomena that occured afterward. Nevertheless, following single scenario of disaster to create a disaster emergency plan might lead to an ...
M. F.N. Maghfiroh, S. Hanaoka
doaj +1 more source
Nepal Journal of Neuroscience, 2021 Introduction: Intracerebral hemorrhage (ICH) is a potentially devastating neurologic emergency with long-term functional independence achieved in only limited patients with good prognostic factors. The objective of this study is toidentify the predictors
Somraj Lamichhane +3 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
BUILDING A TSUNAMI DISASTER RESILIENT COASTAL COMMUNITY IN SRI LANKA [PDF]
Science of Tsunami Hazards, 2020 Natural disasters are inevitable, but strategic planning could alleviate or ameliorate their adverse impacts. The frequency of natural disasters in Sri Lanka has risen over the past few decades, thus the number of disaster-affected communities ...
Kaumadi Abeyweera, Akihiko Hokugo
doaj