Results 61 to 70 of about 139,792 (293)

Laboratory investigation of daily food intake and gut evacuation in larvae of African catfish Clarias gariepinus under different feeding conditions [PDF]

open access: yes, 2010
Temporary accumulation of ascorbic acid 2-sulfate (AAS) was measured to estimate food intake and gut evacuation in larvae of African catfish. Fish larvae were fed decapsulated cysts of Artemia containing AAS.
Verreth, J.A.J.   +11 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

BUILDING A TSUNAMI DISASTER RESILIENT COASTAL COMMUNITY IN SRI LANKA [PDF]

open access: yesScience of Tsunami Hazards, 2020
Natural disasters are inevitable, but strategic planning could alleviate or ameliorate their adverse impacts. The frequency of natural disasters in Sri Lanka has risen over the past few decades, thus the number of disaster-affected communities ...
Kaumadi Abeyweera, Akihiko Hokugo
doaj  

Applying the lessons of the attack on the World Trade Center, 11th September 2001, to the design and use of interactive evacuation simulations [PDF]

open access: yes, 2005
The collapse of buildings, such as terminal 2E at Paris' Charles de Gaule Airport, and of fires, such as the Rhode Island, Station Night Club tragedy, has focused public attention on the safety of large public buildings.
C. W. Johnson, Johnson, C.W.
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Fire safety aspects of refuge floors in supertall buildings with computational fluid dynamics

open access: yesJournal of Civil Engineering and Management, 2009
High‐rise buildings in many big cities in the Far East, including Hong Kong, call for refuge floors as a matter of both practicality and compliance with regulations.
Cheuk Lun Chow, Wan Ki Chow
doaj   +1 more source

Evacuation Simulation under Threat of Wildfire—An Overview of Research, Development, and Knowledge Gaps

open access: yes, 2023
Wildfires have become a common incident over the past decades, and they have been threatening people’s lives and assets. In the communities close to wildlands or wildland–urban interfaces (WUI), these threats become increasingly serious, and in case of
Luís Laím   +7 more
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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