Results 191 to 200 of about 1,765 (298)

Multirobot Collaborative Pursuit Target Robot by Improved MADDPG.

Comput Intell Neurosci, 2022
Zhou X, Zhou S, Mou X, He Y.
europepmc   +1 more source

SOLUTION OF SIMPLE PURSUIT-EVASION PROBLEM WHEN EVADER MOVES ON A GIVEN CURVE

We investigate a simple motion pursuit-evasion differential game of one Pursuer and one Evader. Maximal speeds of the players are equal. The Evader moves along a given curve without self-intersection.
ATAMURAT SH. KUCHKAROV
core  

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Multidrug efflux in Gram-negative bacteria: structural modifications in active compounds leading to efflux pump avoidance. [PDF]

NPJ Antimicrob Resist
Gurvic D, Zachariae U.
europepmc   +1 more source

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

Advanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang, Chengfei Jiang, April W. Mao, Qi Sun, Yijun Lu, Jingjing Wei, Jamie L. Inman, Susan E. Celniker, Antoine M. Snijders, David W. Threadgill, Allan Balmain, Bo Hang, Hang Chang, Lei Wang, Jian‐Hua Mao   +14 more
wiley   +1 more source

Andes virus from the 2026 <i>MV Hondius</i> outbreak does not show enhanced entry into human cells. [PDF]

Emerg Microbes Infect
Carrascosa-Sàez M, Arce R, Dufloo J, Sanjuán R.   +3 more
europepmc   +1 more source

Repetitive nociceptive stimulation elicits complex behavioral changes in Hirudo: evidence of arousal and motivational adaptations.

J Exp Biol, 2023
Hoynoski J, Dohn J, Franzen AD, Burrell BD.   +3 more
europepmc   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Balancing harm and harmony: Evolutionary dynamics between gut microbiota-derived flagellin and TLR5-mediated host immunity and metabolism. [PDF]

Virulence
Seo B, Lim MY.
europepmc   +1 more source

Catching evaders [PDF]

, 2019
openaire   +1 more source