Results 101 to 110 of about 2,034,522 (291)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

QUADAS e STARD: avaliação da qualidade de estudos de acurácia de testes diagnósticos

Revista de Saúde Pública
OBJETIVO: Comparar duas abordagens baseadas em critérios do Quality Assessment of Diagnostic Accuracy Studies (QUADAS) e do Standards for Reporting Studies of Diagnostic Accuracy (STARD) na avaliação de qualidade de estudos de validação do teste rápido ...
Maria Regina Fernandes de Oliveira, Almério de Castro Gomes, Cristiana Maria Toscano   +2 more
doaj  

EveTAR: Building a Large-Scale Multi-Task Test Collection over Arabic Tweets

, 2017
This article introduces a new language-independent approach for creating a large-scale high-quality test collection of tweets that supports multiple information retrieval (IR) tasks without running a shared-task campaign.
A Bruns, AM Azmi, BS Wasike, D Bodoff, D Elsweiler, Hind Almerekhi, J Benhardus, JL Fleiss, JR Landis, K Darwish, M Efron, M Rowe, M Sanderson, Maram Hasanain, Mucahid Kutlu, Reem Suwaileh, RL Brennan, Tamer Elsayed, W Magdy, Zhang Y   +19 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The Evaluation of When English Rings a Bell (Revised Edition): Teachers' Perspectives [PDF]

, 2015
This study was done to find out the teachers` opinions regarding the coursebook, When English Rings A Bell (revised edition), in terms of (1) the coursebook`s language content, (2) the presentation of English skills in the coursebook, and (3) the ...
Faujiah, E. (Eva), Floris, F. D. (Flora)
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Issues in Sports Forecasting [PDF]

A great amount of effort is spent in forecasting the outcome of sporting events, but few papers have focused exclusively on the characteristics of sports forecasts. Rather, many papers have been written about the efficiency of sports betting markets.
David Sendor, Herman O. Stekler, Richard Verlander   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Building Competence: Expectations, Experience, and Evaluation of E-Government as a Topic in Administration Programs at the TH Wildau – A Case Study (Invited Paper)

Journal of Systemics, Cybernetics and Informatics, 2020
The paper presents two new degree programs in administra-tion from the German university system as well as lectures focusing on e-government and the questions of how competence in this area can be created and what the students' expectations and experience are of the IT Planning Council's modernization projects.
openaire   +1 more source

Classification of Empirical Work on Sales Promotion: A Synthesis for Managerial Decision Making [PDF]

Sales Promotion activities have gained strategic focus as markets are getting complex and competitive. Key managerial concerns in this area are budget allocation across elements of promotions as well as trade vis.
Mehta Bijal, Vyas Preeta H
core