Results 131 to 140 of about 2,034,522 (291)
A Broad Evaluation of the Tor English Content Ecosystem
Tor is among most well-known dark net in the world. It has noble uses, including as a platform for free speech and information dissemination under the guise of true anonymity, but may be culturally better known as a conduit for criminal activity and as a
Allahyari, Mehdi +3 more
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
In today's era of enormous text data, topic modeling is emerging as a revolutionary tool in natural language processing. From the corpus of scientific research articles to social media posts and newspaper headlines, topic modeling is employed in several ...
Pratima Kumari +6 more
doaj +1 more source
Graduate Catalog, 2004-2005 [PDF]
https://scholar.valpo.edu/gradcatalogs/1031/thumbnail ...
Valparaiso University
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Simulation technology use in disaster medicine education and training: a scoping review
BackgroundDisaster medicine (DM) education has increasingly turned to simulation technologies to address the limitations of traditional training methods.
José García Ulerio +10 more
doaj +1 more source
Optimization of stand-alone photovoltaic system by implementing fuzzy logic MPPT controller [PDF]
A photovoltaic (PV) generator is a nonlinear device having insolation-dependent volt-ampere characteristics. Since the maximum-power point varies with solar insolation, it is difficult to achieve an optimum matching that is valid for all insolation
Hashim, Mokhtar
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

