Results 51 to 60 of about 305,125 (284)

Efectos de la tasa de evasión de impuesto de renta sobre el crecimiento económico en Colombia (2002-2016) [PDF]

, 2019
Trabajo de investigaciónEn este trabajo busca determinar el impacto de la evasión del impuesto de renta sobre el crecimiento económico. Para ello, en primer lugar, se realiza una exploración literaria y teórica de autores nacionales e internacionales ...
Escobar-Mariño, Nicolas, Rodríguez-Vinasco, Andrés Felipe   +1 more
core  

Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion

Nature Communications, 2022
Glioblastoma multiforme (GBM) remains the top challenge to radiotherapy with only 25% one-year survival after diagnosis. Here, we reveal that co-enhancement of mitochondrial fatty acid oxidation (FAO) enzymes (CPT1A, CPT2 and ACAD9) and immune checkpoint
Nian Jiang, B. Xie, W. Xiao, M. Fan, Shanxiu Xu, Yixin Duan, Yamah Hamsafar, A. Evans, Jie Huang, Wei-Bing Zhou, Xuelei Lin, Ningrong Ye, Siyi Wanggou, W. Chen, Di Jing, R. Fragoso, B. Dugger, P. F. Wilson, M. Coleman, S. Xia, Xuejun Li, Lunqun Sun, A. Monjazeb, Aijun Wang, W. Murphy, H. Kung, Kit S. Lam, Hong-Wu Chen, Jian Jian Li   +28 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Elusión fiscal e intercambio de información tributaria entre Estados [PDF]

, 2008
La relevancia que en la actualidad tiene el intercambio de información tributaria entre distintos Estados hunde sus raíces en la necesidad de encontrar mecanismos útiles y eficaces que permitan combatir el fraude, la evasión e incluso la elusión fiscal ...
Martínez Giner, Luis Alfonso
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

LOS FALLOS PENALES POR INASISTENCIA ALIMENTARIA Un desfase entre la ley y la práctica judicial

Revista IUSTA, 2016
Las decisiones judiciales producidas por los jueces acerca del delito de inasistencia alimentaria, se caracterizan por salir de los límites considerados por el legislador.
MANUEL FERNANDO MOYA VARGAS
doaj   +1 more source

Paraísos fiscales, riqueza offshore y evasión fiscal. Una estimación para España (1980-2013) [PDF]

, 2016
La problemática de los paraísos fiscales es un fenómeno cada vez más relevante en el funcionamiento de la economía mundial y está estrechamente relacionado con las crisis financieras y el aumento de la desigualdad.
Peramo, Juan Carlos
core   +3 more sources

SARS-COV-2 Variants: Differences and Potential of Immune Evasion

Frontiers in Cellular and Infection Microbiology, 2022
The structural spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing antibody recognition.
S. Hirabara, T.D.A. Serdan, R. Gorjão, L. N. Masi, T. Pithon-Curi, D. Covas, R. Curi, E. Durigon   +7 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source