Results 61 to 70 of about 250,617 (285)
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Un análisis experimental de la evasión fiscal [PDF]
Este trabajo busca establecer un puente entre los resultados predichos por la teoría de juegos aplicados a la evasión fiscal y los resultados que los experimentos y los datos sugieren.
Fatás Juberías, Enrique +1 more
core
Videojugadores del League of Legends : el papel de la pasión en el uso abusivo y en el rendimiento [PDF]
Los juegos Massively Multiplayer Online Role Playing Games (MMORPG) han suscitado preocupación por su potencial adictivo. Los Multiplayer Online Battle Arena (MOBA) son un nuevo género poco estudiado, pero que goza de gran popularidad, en el que prima el
Bertran Martí, Enric +1 more
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
La elección de la forma de explotación agrícola con costes de transacción [PDF]
This paper intends to generalize the SANDMO'S model on evasion and optimal taxation (Journal of Public Economics, 1981, Vol. 16) in two directions.
Datta, Samar K. +2 more
core +5 more sources
La planificación tributaria internacional. The international tax planning
La planificación tributaria internacional se ha desarrollado fundamentada en la globalización y tiene su principal asidero en los múltiples beneficios que el propio legislador ha incorporado en la legislación, en su afán de atraer a los países inversión ...
Romeo Carpio Rivera
doaj +1 more source
Obra ressenyada: Yi-Fu TUAN, Escapismo. Formas de evasión en el mundo actual.
Nogué i Font, Joan,
core
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source

