Results 131 to 140 of about 49,849 (236)

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

Advanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song, Meng Wang, Xingyu Wu, Meng Cai, Bowen Li, Qi Wang, Xiaodong Guan, Qi Ding, Ruobing Wang, Hui Wang   +9 more
wiley   +1 more source

A negotiation method for cooperative collision avoidance between ships in mixed navigation scenarios: model construction, strategy driving, and unilateral learning

Brodogradnja
With the gradual development of Maritime Autonomous Surface Ships (MASS), sea traffic is expected to remain in mixed navigation scenarios where autonomous and conventional ships operate concurrently.
Xiaohui Wang, Yingjun Zhang, Shaobo Wang, Zhiyuan Jiang   +3 more
doaj   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Cansancio y somnolencia durante el desempeño laboral de los conductores interprovinciales: experiencia peruana y planteamiento de propuestas Tiredness and sleepiness in rural bus drivers during their job performance: Peruvian experience and proposals

Revista Peruana de Medicina Experimental y Salud Pública, 2010
La información indica que los accidentes de tránsito causados por somnolencia o cansancio de los conductores de ómnibus son frecuentes en nuestro país.
Jorge Rey de Castro, Edmundo Rosales-Mayor   +1 more
doaj  

Dual‐Gene Edited Extracellular Vesicles Remodel the Redox Homeostasis to Inhibit Ferroptosis in Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is driven by ferroptosis of nucleus pulposus cells (NPCs) as a core pathological mechanism. Nucleus pulposus progenitor cells (NPPCs), exhibiting stem cell‐like properties, yield extracellular vesicles (PEVs) with high affinity for NPCs and enable targeted phenotypic regulation.
Jing Yan, Yazhou Lin, Shuo Miao, Minghao Chao, Chengbai Dai, Ziwen Hao, Rui Chen, Ming Guan, Bin Pan, Fenglei Gao, Quan Zhou   +10 more
wiley   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

Advanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan, Youdan Zhang, Zhujun Wang, Huatao Tang, Huiping Liu, Zi Chen, Shuai Liu, Jiayi Shi, Lu Peng, Youming Hou   +9 more
wiley   +1 more source

Analysis of the success rate of evasive manoeuvres in American football

Title: Analysis of the Success Rate of Evasive Maneuvers in American Football Objectives: The aim of this study was to determine the success rate of evasive maneuvers used by American football players after catching a pass in order to evade an opponent ...
Ženka, Ondřej
core  

Gregarious Behaviour of Evasive Prey [PDF]

Gregarious behavior of potential prey was explained by Hamilton (1971) on the basis of risk-sharing: The probability of being picked up by a predator is small when one makes part of a large aggregate of prey.
Avner Shaked, Ilan Eshel, Emilia Sansone
core  

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

A New Methodology for Optimizing Evasive Maneuvers Under Uncertainty in the Extended Two-Dimensional Pursuer/Evader Problem

, 1997
: Traditional analytic or controltheoretic solutions to the problem of optimizing evasive maneuvers in the extended two-dimensional pursuer/evader problem require the evader to execute specific sequences of maneuvers at precise pursuer/evader distances ...
Oscar N. Garcia, Frank W. Moore
core