Results 91 to 100 of about 108,897 (285)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Diminishing mangrove forest structures in Davao City, Philippines
Davao Research JournalThe decline of mangrove coverage across the Philippines to 50% of its original coverage in present years has, led to significant reductions of ecological functions to fisheries and benefits to man.
John Glen P. Seniel +2 more
doaj +1 more source
Acta Botânica Brasílica, 2010 We examined the species abundance distribution (SAD) of plant communities in: (1) a wet grassland, waterlogged throughout most of the year; (2) a seasonal savanna, with an annual dry season; and (3) a hyperseasonal savanna, with alternating drought and ...
Igor Aurélio Silva +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Folia Oecologica, 2020 Urbanization is a form of pervasive human-induced disturbance. We tested the effectiveness of Abundance/Biomass Comparisons (ABC) as an approach in detecting stress due to landscape urbanization in large small mammal assemblages obtained from pellets of ...
di Bagno Ermellina +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Известия ТИНРО, 2014 The Bering Sea, Okhotsk Sea, Japan/East Sea and adjacent waters of the Pacific Ocean (mainly within EEZ of Russia) are compared by abundance of pelagic and benthic macrofauna, its species richness, evenness, diversity, and mean weight of animals using ...
Igor V. Volvenko
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source