Results 111 to 120 of about 7,416 (189)
Liquid–Liquid Phase Separation in Major Hallmarks of Cancer
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie +10 more
wiley +1 more source
T Cell Exhaustion in Hepatocellular Carcinoma: A Substantial Barrier in Immunotherapy
ABSTRACT Hepatocellular carcinoma (HCC), accounting for over 90% of primary liver cancers, remains a major global challenge for healthcare professionals. While immunotherapy has transformed the landscape of cancer treatment, its success is often limited by immune resistance, particularly through T cell exhaustion which remains a major barrier to ...
Kosar Nouri +7 more
wiley +1 more source
ABSTRACT We learn from our mistakes, often through external feedback. However, there is little research into the intertwining of a student's neural error‐monitoring and their monitoring of external feedback (feedback‐monitoring), or how error feedback received from external sources is experienced emotionally.
Minkang Kim +2 more
wiley +1 more source
ABSTRACT Auditory rhythm perception involves bottom‐up encoding of timing information and top‐down maintenance of a particular interpretation, such as grouping beats to form meter. Top‐down meter perception can be measured using electroencephalographic responses like mismatch negativity (MMN), P3a, and Steady‐State Evoked Potentials (SSEPs). Previously
Erica Flaten +2 more
wiley +1 more source
Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano +6 more
wiley +1 more source
Enhancer‐dependent gene regulation in space, time, and malignancies
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum +2 more
wiley +1 more source
Distress Intolerance Is Associated With a Greater Reward Positivity to Aversive Avoidance Feedback [PDF]
ABSTRACT Research indicates that the reward positivity (RewP) can be elicited by both appetitive gain (e.g., winning money) and aversive outcome avoidance (e.g., safety from a noise blast). Yet, little work has linked these differential reward responses with avoidance‐related psychopathology risk factors.
Albanese B +5 more
europepmc +2 more sources
XLNTBrain Cognitive Performance With Event Related Potential P300
openaire +1 more source
Analysis of P300 Evoked Potentials to Determine Pilot Cognitive States. [PDF]
Rodríguez-Bermúdez G +2 more
europepmc +1 more source
The performance of mind: from movement, mental states, and consciousness. [PDF]
Cheron G, Cebolla AM.
europepmc +1 more source

