Results 151 to 160 of about 411,327 (250)

The universal role of adaptive transcription in health and disease

The FEBS Journal, EarlyView.
Adaptive transcription via molecules such as CREB, MEF2, SRF, AP1, Nr4a1, and Egr1 constitutes a universal mechanism for directed cell state transitions in health and disease. These molecules are involved in physiological adaptation processes, pathological maladaptations, curative adaptations, and development of resistance to treatment.
Thomas Lissek
wiley   +1 more source

Building Brain Invaders: EEG data of an experimental validation [PDF]

arXiv, 2019
We describe the experimental procedures for a dataset that we have made publicly available at https://doi.org/10.5281/zenodo.2649006 in mat and csv formats. This dataset contains electroencephalographic (EEG) recordings of 25 subjects testing the Brain Invaders (Congedo, 2011), a visual P300 Brain-Computer Interface inspired by the famous vintage video
arxiv  

Versatile roles of disordered transcription factor effector domains in transcriptional regulation

The FEBS Journal, EarlyView.
Disordered effector domains (EDs) of transcription factors (TFs) play versatile roles in transcriptional regulation. These include mediating protein–protein interactions with protein complexes like, facilitating condensate formation to enhance transcriptional efficiency, modulating DNA‐binding specificity through genome scanning, and serving as hubs ...
Rhea R. Datta, Dilan Akdogan, Elif B. Tezcan, Pinar Onal   +3 more
wiley   +1 more source

Epigenetic control of cell identities from epiblast to gastrulation

The FEBS Journal, EarlyView.
In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley   +1 more source

Recent Long‐Distance‐Dispersal Explains the Range Disjunction of the Old‐Word Cockleburs (Xanthium strumarium)

Journal of Biogeography, EarlyView.
ABSTRACT Aim In the present study, we focused in addressing questions concerning the biogeographic history of Xanthium strumarium, an Old World native species whose close relatives are generally all native to the American continent. Location The species distribution covers the Eurasian continent and some African regions and close islands.
Eleonora Manzo, Salvatore Tomasello
wiley   +1 more source

Effect of crystallization temperature on the flexural strength of lithium disilicate glass ceramics

Journal of Prosthodontics, EarlyView.
Abstract Purpose This pilot study aimed to compare the flexural strength of Amber Mill CAD to IPS e.max CAD and to determine the impact of different crystallization protocols on the flexural strength of Amber Mill CAD ceramics. Materials and Methods Amber Mill CAD ceramic blocks of a known Vita Classic shade were selected for testing against control ...
Mohammed A. Akl, Hashem Dashtti, Jood Akl, Fengyuan Zheng   +3 more
wiley   +1 more source

The neuroscience of dissociative amnesia and repressed memory: Premature conclusions and unanswered questions

Legal and Criminological Psychology, EarlyView.
Abstract Purpose A heated debate exists on whether traumatic memories can be dissociated or repressed. One way in which researchers have attempted to prove the existence of dissociative amnesia or repressed memory is to examine whether claims of amnesia for traumatic events are associated with specific neural markers.
Henry Otgaar, Mark L. Howe, Lawrence Patihis, Ivan Mangiulli, Olivier Dodier, Rafaële Huntjens, Elisa Krackow, Marko Jelicic, Steven Jay Lynn   +8 more
wiley   +1 more source

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

Neuropathology, EarlyView.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata, Ikuko Kataoka, Yukinori Okamura, Kumiko Murakami, Yoichiro Kato, Tomoko Yamamoto, Kenta Masui   +6 more
wiley   +1 more source

On the use of the P300 as a tool for cognitive processing assessment in healthy aging: A review

Dementia & Neuropsychologia
Changes in patterns of performance for the cognitive functions of memory, processing speed, and focused attention are expected in old age. Objective: The main goal of this systematic review was to analyze the use of ERP in healthy elderly in studies ...
Sofia Cristina Iost Pavarini, Allan Gustavo Brigola, Bruna Moretti Luchesi, Érica Nestor Souza, Estefani Serafim Rossetti, Francisco José Fraga, Letícia Pimenta Costa Guarisco, Marélli Terassi, Nathalia Alves Oliveira, Priscilla Hortense, Renata Valle Pedroso, Ana Carolina Ottaviani   +11 more
doaj   +1 more source

Cognitive assessment in multiple sclerosis patients: electrophysiological and subjective studies

The Egyptian Journal of Otolaryngology
Background Multiple sclerosis (MS) is a persistent inflammatory condition affecting the central nervous system, often associated with cognitive impairment.
Abeer Elsayed, Mona Kotait, Salma Ragab, Takwa Gabr   +3 more
doaj   +1 more source