Results 151 to 160 of about 8,670,117 (259)

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy, Emmanuel Anyachukwu Irondi, Abdulazeez Olamilekan Elemosho, Emmanuel Oladipo Ajani   +3 more
wiley   +1 more source

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1597-1609, September 2026.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito, Marieli Mariano Gonçalves Dias, Gabriel Ernesto Jara, Thayná Mendonça Avelino, Giovanna Blazutti Elias, Paulo Sergio Lopes de Oliveira, Ana Carolina Migliorini Figueira   +6 more
wiley   +1 more source

A longitudinal, event-related potential pilot study of adult obsessive-compulsive disorder with 1-year follow-up

Neuropsychiatric Disease and Treatment, 2016
Kazuhiko Yamamuro,1 Koji Okada,2 Naoko Kishimoto,1 Toyosaku Ota,1 Junzo Iida,3 Toshifumi Kishimoto1 1Department of Psychiatry, Nara Medical University School of Medicine, 2Department of Psychiatry, Jingumaecocorono-Clinic, 3Faculty of Nursing, Nara ...
Yamamuro K, Okada K, Kishimoto N, Ota T, Iida J, Kishimoto T   +5 more
doaj  

Advanced Electrospun Nanofiber Epidermal Electronics for Electrophysiological Monitoring: From Conformal Interfaces to Multimodal Closed‐Loop Systems

Rare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT Epidermal bioelectronics is a transformative technology for continuous health monitoring and human‐computer interaction. However, the mechanical and physiological mismatch at the skin–device interface limits its long‐term application. Electrospun nanofiber membranes (ENMs), with their unique three‐dimensional hierarchical porous network and ...
Jiahua Ni, Jing Lu, Nianzhe Wu, Jiahui Tang, Tiantian Chen, Xiaonong Zhang, Wenhui Wang, Zhe Zhao   +7 more
wiley   +1 more source

Oxygenaging: A Physiological Framework for Geroscience

Aging Cell, Volume 25, Issue 9, September 2026.
Mechanisms of aging disrupt oxygen homeostasis through three converging processes: oxygen‐cascade impairment, microvascular dysfunction, and molecular maladaptation. “Oxygenaging” integrates these domains to explain how declining oxygen delivery and utilization drive mitochondrial instability and amplify the effect of the hallmarks of aging.
Stefano Donega, Kenneth W. Fishbein, Paolo Dominelli, Allison B. Herman, Rafael de Cabo, Myriam Gorospe, Luigi Ferrucci   +6 more
wiley   +1 more source

KPNA2 Drives Immunosuppression in Ovarian Cancer via CCL2/CCR2‐Dependent MDSC Recruitment

Cancer Science, Volume 117, Issue 9, Page 2461-2479, September 2026.
KPNA2 drives intratumoral MDSC accumulation and immunosuppression in ovarian cancer via the NF‐κB/CCL2/CCR2 axis. Mechanistically, KPNA2 facilitates NF‐κB/p65 nuclear translocation and induces CCL2 transcription, recruiting MDSCs to establish an immunosuppressive microenvironment.
Qingli Li, Jitong Zhao, Lu Yang, Lin Li, Ce Bian, Tao Yi, Huiqiong Huang, Gang Zheng, Xiaojuan Lin   +8 more
wiley   +1 more source

ADSC‐Derived CCL8 Regulates HIF‐1α Signaling and Promotes Colorectal Cancer Progression in a 3D Coculture Platform

Cancer Science, Volume 117, Issue 9, Page 2480-2495, September 2026.
Schematic illustration showing how CRC‐associated ADSC‐derived CCL8 promotes colorectal cancer cell migration through ERK/HIF‐1α signaling in a 3D coculture platform. ABSTRACT This study aimed to recapitulate adipose‐tumor interactions within the colorectal cancer (CRC) tumor microenvironment (TME) and to elucidate the role of adipose‐derived stem ...
Jeong‐Eun Yun, Yeseon Son, Jieun Seo, Ki Yong Hong, Junji Fukuda, Do‐Won Jeong, Jong‐Wan Park, Yang‐Sook Chun   +7 more
wiley   +1 more source

Electrophysiological Correlates of Encoding Indicate Altered Processing but Comparable Subsequent Memory Effects Across Virtual Reality and Desktop‐Based Conditions

European Journal of Neuroscience, Volume 64, Issue 5, September 2026.
The study examined whether successful object encoding relies on comparable or modality‐specific neural processes across immersive virtual reality (VR) and desktop (PC) presentation. Encoding‐related EEG activity was analyzed in a subsequent memory paradigm using ERP and oscillatory markers.
Joanna Kisker, Merle Sagehorn, Thomas Gruber   +2 more
wiley   +1 more source

Is brain activity observable that leads to an evaluation of a probability of 0.5 that is different from 0.5 in binary lottery choices? [PDF]

This paper focuses on the problem of probability weighing in the evaluation of lotteries. According to Prospect Theory a probability of 0.5 has a weight of smaller than 0.5.
Bodo Vogt, Marcus Heldmann, Ralf Morgenstern, Thomas Münte   +3 more
core  

Effects of caffeine on event-related potentials (P300) and cognitive performance: protocol for a systematic review

This submission is a systematic review protocol for the effects of caffeine on event-related potentials and cognitive performance. This review aims to summarize the studies focused on the effects of caffeine on ERPs, paying special attention to ...
Joana O. Pinto, Prune Mazer, Beatriz Barbosa Pinho   +2 more
core   +1 more source