Results 61 to 70 of about 7,416 (189)

Forensic Application of Objective Assessment on Visual Acuity by ERP [PDF]

open access: yesFayixue Zazhi, 2017
Objective To explore the composition characteristic of event related potential (ERP) in different visual acuity levels, and to provide theoretical basis for the objective assessment of visual acuity.
LUO BIN, JI MENG-MENG, MENG HUAN-HUAN, ET AL.
doaj   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

open access: yesAdvanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin   +5 more
wiley   +1 more source

Auditory Processing in Stuttering Children: Behavioral and Electrophysiological Assessments

open access: yesInternational Archives of Otorhinolaryngology
Introduction Stuttering is a human communication disorder characterized by involuntary interruptions to speech flow. Electrophysiological tests and behavioral evaluations allow the neuroaudiological processes involved in stuttering to be ...
Letícia Gregory   +5 more
doaj   +1 more source

Compensation Response to Hepatic Gluconeogenesis via β‐Hydroxybutyrylation of FBP1 and PCK1 in Dairy Cows

open access: yesAnimal Research and One Health, EarlyView.
(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng   +6 more
wiley   +1 more source

EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease

open access: yesExploration, EarlyView.
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren   +15 more
wiley   +1 more source

Heat Transfer Performance of Biphilic Surfaces With Diatomite‐Based Composite Coatings in a Closed Thermosyphon System

open access: yesHeat Transfer, EarlyView.
ABSTRACT This study investigates the thermal performance of innovative biphilic boiling surfaces designed for CPU cooling applications using a two‐phase closed thermosyphon (TPCT) system. The surfaces were fabricated by applying composite coatings—comprising epoxy resin and diatomite particles functionalized with APTES and PFOTS silanes— onto Al1050 ...
José Pereira   +3 more
wiley   +1 more source

Age-changed normative auditory event-related potential value in children in Taiwan

open access: yesJournal of the Formosan Medical Association, 2012
Event-related potentials (ERPs) reflect higher cortical function and the P3 (P300) wave has been associated with various sensory, cognitive, and attention processes.
Min-Lan Tsai   +3 more
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Behavioral and Electrophysiological Assessment of Adults Who Underwent Cochlear Implantation After Hearing Aid Experience*

open access: yesInternational Archives of Otorhinolaryngology, 2020
Introduction Cochlear implantation has been considered a viable option to restore hearing perception in adults with severe to profound postlingual hearing loss.
Victor Goiris Calderaro   +5 more
doaj   +1 more source

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