Results 91 to 100 of about 3,528 (219)

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Optimizing control efficiency in discrete-time multi-agent systems via event-triggered containment techniques combining disturbance handling and input delay management

Heliyon
The goal of this paper is to mitigate disturbances and input delays while optimizing controller actuation updates for discrete-time multi-agent systems through the use of an event-triggered confinement control system, especially in resource-constrained ...
Hanen Louati, Azmat Ullah Khan Niazi, Mhassen. E.E. Dalam, Waqar Ul Hassan, Khawer Hameed Khan, Mohammed Alhagyan   +5 more
doaj   +1 more source

Distributed Event-Triggered Control of Multiagent Systems with General Linear Dynamics

Journal of Control Science and Engineering, 2014
This paper discusses the event-triggered consensus problem of multiagent systems. To investigate distributed event-triggering strategies applied to general linear dynamics, we employ a dynamic controller to convert the general linear dynamic to the ...
Xieyan Zhang, Jing Zhang
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Output-based event-triggered control with Guaranteed ℒ∞-gain and improved event-triggering.

, 2010
Most event-triggered controllers available nowadays are based on static state-feedback controllers. As in many control applications the full state is not available for feedback, it is the objective of this paper to propose event-triggered dynamical output-based controllers.
M. C. F. Donkers, W. P. M. H. Heemels
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Mixed Time/Event-Triggered Model Predictive Tracking Control for Networked Mobile Robots

IEEE Access
Focusing on the tracking control challenges in networked mobile robot systems, this research formulates a mixed time/event-triggered model predictive control (MPC) method.
Huixin Liu, Yonghua Lai, Hongsong Lian, Guobin Wang, Dongsheng Zheng   +4 more
doaj   +1 more source

Global Robust Exponential Synchronization of Multiple Uncertain Neural Networks Subject to Event-Triggered Strategy

Complexity, 2019
This paper proposes the event-triggered strategy (ETS) for multiple neural networks (NNs) with parameter uncertainty and time delay. By establishing event-triggered mechanism and using matrix inequality techniques, several sufficient criteria are ...
Jin-E Zhang, Huan Liu
doaj   +1 more source