Results 71 to 80 of about 3,528 (219)

Decentralized Non-Fragile Event-Triggered ${{H}_{\infty}}$ Filtering for Large-Scaled Power System Based on T-S Fuzzy Model

open access: yesIEEE Access, 2018
Considering the characteristics of the large-scaled power system and the communication networks, this paper studies the decentralized non-fragile H∞ filtering for the large-scaled power system with the event-triggered strategy.
Liangliang Zhang, Hongbin Zhang, Hui Gao
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Dynamic Event-Triggered Output Feedback Control for Switched Systems via Switched Lyapunov Functions

open access: yesApplied Sciences
This study carries out the research on event-triggered output feedback control tailored for discrete-time switched linear systems. A dynamic event-triggered mechanism (DETM) is utilized to mitigate the triggering frequency.
Xinyue Wang, Yanhui Tong, Yuyuan Li
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Dynamic event-triggered consensus of multi-agent systems with trigger-dependent communication delay

open access: yesJournal of King Saud University: Computer and Information Sciences
This paper discusses the consensus problem of discrete-time multi-agent systems with communication delay under an event-triggered control protocol. To reduce the network communication burden, a dynamic event-triggered mechanism is designed to judge ...
Mengshen Chen   +3 more
doaj   +1 more source

Event-Triggered Control of Grid-Connected Inverters Based on LPV Model Approach

open access: yesEnergies
This study aims to develop an event-triggered control strategy of grid-connected inverters, based on the linear parameter-varying (LPV) modeling approach.
Wensheng Luo   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Consensus Control of Time-Varying Multi-Agent Systems via Event-Triggered Strategy and Its Application

open access: yesIEEE Access
This paper presents the first investigation into the consensus problem of linear time-varying multi-agent systems employing an event-triggered communication scheme.
Wensheng Chi   +4 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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