Results 81 to 90 of about 1,228,057 (342)

Di-hadron azimuthal correlation and Mach-like cone structure in parton/hadron transport model

open access: yes, 2006
In the framework of a multi-phase transport model (AMPT) with both partonic and hadronic interactions, azimuthal correlations between trigger particles and associated scattering particles have been studied by the mixing-event technique.
Adams   +59 more
core   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Observer–Based Sliding–Mode Fault–Tolerant Consistent Control for Hybrid Event–Triggered Multi–Agent Systems

open access: yesInternational Journal of Applied Mathematics and Computer Science
An observer-based hybrid event-triggered sliding mode fault-tolerant consistent control strategy is proposed for actuator faults in nonlinear second-order leader–follower multi-agent systems.
Xia Dexian, Fu Xingjian
doaj   +1 more source

Magnitude-Dependent Omori Law: Empirical Study and Theory

open access: yes, 2004
We propose a new physically-based ``multifractal stress activation'' model of earthquake interaction and triggering based on two simple ingredients: (i) a seismic rupture results from activated processes giving an exponential dependence on the local ...
Ouillon, G., Sornette, D.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Event‐triggered attack detection and state estimation based on Gaussian mixture model

open access: yesIET Cyber-Physical Systems
Under the framework of event‐triggered transmission mechanism, the problem of attack detection and state estimation of multi‐sensor linear time‐invariant systems under static attacks is considered.
Lu Jiang   +5 more
doaj   +1 more source

Event-triggered gain scheduling of reaction-diffusion PDEs

open access: yes, 2020
This paper deals with the problem of boundary stabilization of 1D reaction-diffusion PDEs with a time- and space- varying reaction coefficient. The boundary control design relies on the backstepping approach.
Espitia, Nicolas   +2 more
core  

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