Results 51 to 60 of about 122,985 (297)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Inter-event interval microscopy for event cameras

Photonics Research
Event cameras detect intensity changes rather than absolute intensity, recording variations as a stream of “event.” Intensity reconstruction from these sparse events remains a significant challenge. Previous approaches focused on transforming motion-induced events into videos or achieving intensity imaging for static scenes through modulation devices ...
Changqing Su, Yanqin Chen, Zihan Lin, Zhen Cheng, You Zhou, Bo Xiong, Zhaofei Yu, Tiejun Huang   +7 more
openaire   +2 more sources

Events-To-Video: Bringing Modern Computer Vision to Event Cameras [PDF]

2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2019
Event cameras are novel sensors that report brightness changes in the form of asynchronous “events” instead of intensity frames. They have significant advantages over conventional cameras: high temporal resolution, high dynamic range, and no motion blur.
Henri Rebecq, René Ranftl, Vladlen Koltun, Davide Scaramuzza 0001   +3 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Compressive event camera

Optics Express
In this paper, we present a method for reconstructing video from event data alone captured by an event camera. We employ point-spread-function engineering in the imaging optics to compress spatiotemporal information into each event. Dynamic scenes are reconstructed solely from the sparse, signed-polarity event data using a compressive sensing algorithm.
Yudai Yokoyama, Manato Yo, Otoya Shigematsu, Ryoichi Horisaki   +3 more
openaire   +2 more sources

Motion-Aware Optical Camera Communication With Event Cameras

IEEE Robotics and Automation Letters
As the ubiquity of smart mobile devices continues to rise, Optical Camera Communication systems have gained more attention as a solution for efficient and private data streaming. This system utilizes optical cameras to receive data from digital screens via visible light. Despite their promise, most of them are hindered by dynamic factors such as screen
Hang Su, Ling Gao 0001, Tao Liu, Laurent Kneip   +3 more
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Neuromorphic Driver Monitoring Systems: A Proof-of-Concept for Yawn Detection and Seatbelt State Detection Using an Event Camera

IEEE Access, 2023
Driver monitoring systems (DMS) are a key component of vehicular safety and essential for the transition from semi-autonomous to fully autonomous driving.
Paul Kielty, Mehdi Sefidgar Dilmaghani, Waseem Shariff, Cian Ryan, Joe Lemley, Peter Corcoran   +5 more
doaj   +1 more source

Bioinspired event-driven collision avoidance algorithm based on optic flow

, 2015
Any mobile agent, whether biological or robotic, needs to avoid collisions with obstacles. Insects, such as bees and flies, use optic flow to estimate the relative nearness to obstacles. Optic flow induced by ego-motion is composed of a translational and
Benosmanz, Ryad, Egelhaaf, Martin, Benosman, Ryad B., Bertrand, Olivier, Milde, Moritz B. (R19881), Chicca, Elisabetta, Olivier J.N. Bertrand, Martin Egelhaaf, Milde, Moritz B, Elisabetta Chicca, Moritz B. Milde, Bertrand, Olivier J N, Ryad Benosmanz   +12 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source