Results 71 to 80 of about 605,381 (249)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Frontiers in Environmental ScienceAs a new generation of urban water management concepts, sponge city (SC) initiative proposed by China plays the pivotal role in mitigating flood risk, combating climate change, and enhancing environmental resilience. The diffusion patterns and mechanisms
Chen Qian, Shupeng Lyu
doaj +1 more source
Changing roles of marriage and family status for labor migration? The case of rural China [PDF]
Demographic ResearchBACKGROUND: China has witnessed a continuous rise of couple migration and family migration. These migration developments possibly signal individuals’ changing considerations of marital and parenthood responsibilities in their migration decisions over ...
Weiwen Lai, Jing Song
doaj +1 more source
An Empirical Study of Promotion Pressure among University Teachers in China Using Event History Analysis. [PDF]
Int J Environ Res Public Health, 2022 Liu X, Zhang L, Ma H, Nan H, Liu R.
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The impact of occupational structures on ethnic and gendered employment gaps: An event history analysis using social security register data. [PDF]
PLoS One, 2021 Vogtenhuber S +3 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Forum: Qualitative Social Research, 2006 With Using Narrative in Social Research Jane ELLIOTT has made an original and very accessible contribution to the methodological literature in social research. The originality of the work lies most of all in its double aim. ELLIOTT not only presents both
Leen Beyers
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source