Results 81 to 90 of about 605,381 (249)
The impact of female employment on fertility in Dakar (Senegal) and Lomé (Togo)
Demographic Research, 2009 This paper investigates the impact of female employment on fertility in two urban contexts in sub-Saharan Africa: Dakar (Senegal) and Lomé (Togo). The hypothesis that wage employment and maternal obligations are incompatible seems to be corroborated
doaj
Economic resources and the first child in Italy: A focus on income and job stability
Demographic Research, 2011 At the turn of the twentieth century Italy registered a lowest-low fertility level, i.e., a total fertility rate of 1.26 children per woman in 2000. In this paper we investigate whether and how in that period economic resources and, in particular, income
Elisabetta Santarelli
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Men's and women's economic activity and first marriage: Jews in Israel, 1987-1995
Demographic Research, 2010 Using both analysis of the effect of lagged economic and current educational characteristics and analysis of life-course changes in these characteristics, this study provides insights into the theoretical debate concerning the relationships between men ...
Liat Raz-Yurovich
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Second births in western Germany and France
Demographic Research, 2006 We compare second birth risks in France and western Germany using data from the Family and Fertility Survey. Second birth risks are higher for highly educated women than for women with lower education in both countries.
Katja Köppen
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source