Results 61 to 70 of about 605,381 (249)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Methods of Event History Analysis in the Assessment of Crisis Impact on Sectors Related with the Real Estate Market in Poland

Folia Oeconomica Stetinensia, 2017
The subject of the article is the use of methods of event history analysis to assess the fall of prices and the subsequent increase of share prices of companies operating in the construction industry, developers (real estate) and building materials ...
Bieszk-Stolorz Beata, Markowicz Iwona
doaj   +1 more source

MULTISTATE DEMOGRAPHY AND EVENT HISTORY ANALYSIS [PDF]

, 1984
In this paper, Michael Hannan explores a merger of two methodologies for the purpose of analyzing the direct and indirect long-run implications of behavioral responses to public policies: multistate demography and life history or event history analysis.
openaire   +2 more sources

Event History Analysis of Factors Affecting Survival of Older Adults in Taiwan. [PDF]

Healthcare (Basel), 2022
Lo YC, Hsu WC, Weng SJ, Tsai YT, Liu SC, Lin CH.   +5 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Crop Straw Resource Utilization as Pilot Policy in China: An Event History Analysis. [PDF]

Int J Environ Res Public Health, 2023
Bai W, Zhang L, Yan L, Wang X, Zhou Z.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Men's and women's migration in coastal Ghana: An event history analysis

Demographic Research, 2010
This article uses life history calendar (LHC) data from coastal Ghana and event history statistical methods to examine inter-regional migration for men and women, focusing on four specific migration types: rural-urban, rural-rural, urban-urban, and urban-
Holly E. Reed, Catherine S. Andrzejewski, Michael J. White   +2 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Governance Quality and Fertility Transition: A Cross-national Study Using World Bank Data [PDF]

تداوم و تغییر اجتماعی
Background and aim: The quality of governance can influence population dynamics. Using a theoretical framework comprised of demographic transition theory, modernization theory, and institutional theory, this study examined the effect of the quality of ...
Fatemeh Torabi, Reza Teimouri Arshad
doaj   +1 more source