Results 141 to 150 of about 1,621,346 (309)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Community involvement in urban design: help or hindrance? [PDF]
, 1999 This paper examines the realities of community involvement in urban design in the context of a study of the West Itchen Neighbourhood of Southampton, a diverse inner city area accommodating some 7,000 households and 18,000 people.
Gregory, Helen, Rowley, Alan
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Two cases of divorce in the town of Arad in the eighteenth century [PDF]
The two documents, which are the subject of the present study, made to share property in the event of divorce, help to form an image on various aspects of daily life, poorly known from other sources: household size, land property, earnings in marriage ...
Ghita, Eugen
core +1 more source
Hearing the student voice : promoting and encouraging the effective use of the student voice to enhance professional development in learning, teaching and assessment within higher education [PDF]
, 2007 This is an ESCalate development project led by Fiona Campbell of Napier University that was completed in 2007. The Hearing the Student Voice project aimed to promote and encourage the use of the student voice to enhance the effectiveness of academic ...
Beasley, Liz +3 more
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Movie-watching evokes ripple-like activity within events and at event boundaries
Nature CommunicationsRipples are fast oscillatory events widely recognized as crucial markers for memory consolidation and neural plasticity. These transient bursts of activity are thought to coordinate information transfer between the hippocampus and neocortical areas ...
Marta Silva +9 more
doaj +1 more source