Results 91 to 100 of about 26,157,371 (278)

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

open access: yesAdvanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu   +6 more
wiley   +1 more source

Why evidence-based dentistry?

open access: yesBrazilian Journal of Oral Sciences, 2015
Evidence-based dentistry will play an important role in dentistry’s future efforts to control the ravages of diseases affecting the orofacial complex. The historical record suggests that human dental care derived from early attempts to retain or replace ...
Gordon D. Douglass
doaj   +1 more source

Evidence-Based Emergency Medicine

open access: yes, 2008
v.658 hal.; ill.; 27 ...
Evidence-Based Emergency Medicine
core  

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

open access: yesAdvanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne   +15 more
wiley   +1 more source

PERAN DIGITALISASI DALAM PERKEMBANGAN IPTEK KEDOKTERAN GIGI SERTA PEMANFAATNYA DI BIDANG PROSTODONSIA [PDF]

open access: yes, 2015
Over the next decade, the role of digitalization in dentistry will have a great impact on clinical practice. The implementation of digitalization in dentistry especially in prosthodontics are as follows: computerazied electrodiagnostic instrumentation on
Rahardjo, Tri Budi W.; Department of Prosthodontics, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430
core   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

open access: yesAdvanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng   +15 more
wiley   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

open access: yesAdvanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore   +6 more
wiley   +1 more source

Economic burden and economic impact of oral diseases in India: A systematic review and meta-analysis

open access: yesJournal of Oral Biology and Craniofacial Research
Objective: To quantify the economic burden and financial impact of oral diseases in India—on individuals, households, the health system, and society—focusing on direct and indirect costs and out-of-pocket expenditure (OOPE).
Vineetha Karuveettil   +3 more
doaj   +1 more source

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