Results 101 to 110 of about 26,157,371 (278)

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

open access: yesAdvanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang   +18 more
wiley   +1 more source

An Assessment of Dentists' Knowledge of Evidence Based Terms

open access: yesJournal of Islamic International Medical College, 2015
Objective: The study was conducted to assess dentists' understanding of terms used in evidence based healthcare. Study Design: Cross-sectional questionnaire based study. Place and Duration of Study: This study was conducted in the department of community
Fareha Liaqat, Muhammad Humza Bin Saeed, Anum Zehra Khan
doaj  

From reviews to real-time: dynamic evidence in dentistry

open access: yes
Background The exponential growth of biomedical literature—over a million new PubMed entries each year—has outpaced traditional evidence-synthesis methods.
Gavrilova, A. V., Galli, C.
core   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian   +8 more
wiley   +1 more source

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

open access: yesAdvanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler   +4 more
wiley   +1 more source

Interaction Between Operator and Assistant Certification Is Associated With Local Recurrence After Laparoscopic Rectal Cancer Surgery: An Ancillary Analysis of the EnSSURE Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
A significant synergistic interaction between operator and assistant certification was associated with a lower risk of local recurrence after laparoscopic rectal cancer surgery. Patients treated by both ESSQS‐qualified operators and assistants had the lowest risk of local recurrence, whereas a single qualification alone was not associated with a ...
Yusuke Sakimura   +114 more
wiley   +1 more source

Evidence Matters (October 2016) [PDF]

open access: yes, 2016
Newsletter of the Center for Evidence-Based Practices at Case Western Reserve Universityhttps://commons.case.edu/evidence-matters/1005/thumbnail ...
Center for Evidence-Based Practices
core   +1 more source

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