Results 101 to 110 of about 259,136 (295)

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

open access: yesAdvanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao   +11 more
wiley   +1 more source

Economic burden and economic impact of oral diseases in India: A systematic review and meta-analysis

open access: yesJournal of Oral Biology and Craniofacial Research
Objective: To quantify the economic burden and financial impact of oral diseases in India—on individuals, households, the health system, and society—focusing on direct and indirect costs and out-of-pocket expenditure (OOPE).
Vineetha Karuveettil   +3 more
doaj   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

open access: yesAdvanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang   +6 more
wiley   +1 more source

An Assessment of Dentists' Knowledge of Evidence Based Terms

open access: yesJournal of Islamic International Medical College, 2015
Objective: The study was conducted to assess dentists' understanding of terms used in evidence based healthcare. Study Design: Cross-sectional questionnaire based study. Place and Duration of Study: This study was conducted in the department of community
Fareha Liaqat, Muhammad Humza Bin Saeed, Anum Zehra Khan
doaj  

Impact of Sensory Adapted Dental Environment on Children with Developmental Disabilities [PDF]

open access: yes, 2018
Purpose: This was a pilot study assessing the impact of a sensory adapted dental environment (SADE) on children with developmental disabilities (DD) receiving routine dental care.
Kim, Gail
core   +1 more source

Systematic Review of Laser and Other Light Therapy for the Management of Oral Mucositis in Cancer Patients [PDF]

open access: yes, 2012
Background The aim of this study was to review the available literature and define clinical practice guidelines for the use of laser and other light therapies for the prevention and treatment of oral mucositis.
Brian Hodgson   +10 more
core   +2 more sources

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

open access: yesAdvanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai   +9 more
wiley   +1 more source

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