Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
The use of next-generation sequencing in personalized medicine [PDF]
arXivThe revolutionary progress in development of next-generation sequencing (NGS) technologies has made it possible to deliver accurate genomic information in a timely manner. Over the past several years, NGS has transformed biomedical and clinical research and found its application in the field of personalized medicine.
arxiv
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Steroids in De Quervain's tenosynovitis. [PDF]
, 1998 Angela Jones
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Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Identification of Traditional Medicinal Plant Leaves Using an effective Deep Learning model and Self-Curated Dataset [PDF]
Medicinal plants have been a key component in producing traditional and modern medicines, especially in the field of Ayurveda, an ancient Indian medical system. Producing these medicines and collecting and extracting the right plant is a crucial step due to the visually similar nature of some plants.
arxiv +1 more source
Many questions cannot be answered by evidence based medicine [PDF]
, 1995 O. Dearlove +3 more
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Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
AI-driven Alternative Medicine: A Novel Approach to Drug Discovery and Repurposing [PDF]
arXivAIAltMed is a cutting-edge platform designed for drug discovery and repurposing. It utilizes Tanimoto similarity to identify structurally similar non-medicinal compounds to known medicinal ones. This preprint introduces AIAltMed, discusses the concept of `AI-driven alternative medicine,' evaluates Tanimoto similarity's advantages and limitations, and ...
arxiv
SMR: Medical Knowledge Graph Embedding for Safe Medicine Recommendation [PDF]
arXiv, 2017 Most of the existing medicine recommendation systems that are mainly based on electronic medical records (EMRs) are significantly assisting doctors to make better clinical decisions benefiting both patients and caregivers. Even though the growth of EMRs is at a lighting fast speed in the era of big data, content limitations in EMRs restrain the existed
arxiv
Evidence-based medicine and the journal club: a cross-sectional survey of participants' views [PDF]
, 1997 James Warner, Micháel J. King
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