Results 141 to 150 of about 172,980,963 (238)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Summary Document: European Emergency Public Health Response to COVID-19
, 2020 The following information resources have been selected by the National Health Library and Knowledge Service Evidence Virtual Team in response to a request to collate the best available evidence and guidance on the following question: emergency public ...
National Health Library and Knowledge Service Evidence Team
core
Evidence and evidence gaps - an introduction. [PDF]
GMS Curr Top Otorhinolaryngol Head Neck Surg, 2016 Dreier G, Löhler J.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Summary Document: Community Testing for COVID-19
, 2020 The following information resources have been selected by the National Health Library and Knowledge Service Evidence Virtual Team in response to a request to collate the best available evidence and guidance on the following question: when should broader ...
National Health Library and Knowledge Service Evidence Team
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Rapid Evidence Review: COVID-19 community testing
, 2020 Any suspected case should be tested for infection with COVID-19. A suspected case is: a patient with acute respiratory illness that is, fever and at least one sign or symptom of respiratory disease: eg cough or shortness of breath; AND with no other ...
National Health Library and Knowledge Service Evidence Team
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures. [PDF]
JACC Cardiovasc IntervGreenbaum AB +20 more
europepmc +1 more source