Results 151 to 160 of about 172,980,963 (238)

Evidence and evidence gaps in tinnitus therapy. [PDF]

GMS Curr Top Otorhinolaryngol Head Neck Surg, 2016
Hesse G.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Combining Statistical Evidence When Evidence Is Measured by Relative Belief. [PDF]

Entropy (Basel)
Evans M.
europepmc   +1 more source

Evidence and Evidence Gaps in Adolescent Health. [PDF]

J Adolesc Health, 2016
Patton G, Temmerman M.
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Putting the substance in substantial evidence: an evidence-based approach to flexible drug regulation. [PDF]

Front Med (Lausanne)
Krebs E, Bubela T, McPhail M, McCabe C, Regier DA.   +4 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Living evidence profile #6.13b: Best-available evidence related to the mpox outbreak

An overview of the best available research evidence from around the world (i.e., evidence syntheses) and local research evidence (i.e., single studies) and, if applicable, a scan of experiences from other countries and from Canadian provinces and ...
Ali, A, Sivanesanathan, T, DeMaio, P, Grewal, E, Loeb, M, Wilson, MG, Mansilla, C, Wang, Q, Whitelaw, H, Bhuiya, AR   +9 more
core  

Replication of null results: Absence of evidence or evidence of absence? [PDF]

Elife
Pawel S, Heyard R, Micheloud C, Held L.
europepmc   +1 more source

Evidence and evidence gaps of laryngeal cancer surgery. [PDF]

GMS Curr Top Otorhinolaryngol Head Neck Surg, 2016
Wiegand S.
europepmc   +1 more source