Results 61 to 70 of about 7,686 (201)

Efecto del tratamiento combinado de estatinas y evolocumab en pacientes con enfermedad arterial periférica

open access: yesRevista Mexicana de Angiología, 2023
Antecedentes: La ateroesclerosis se caracteriza por el depósito de colesterol y endurecimiento del endotelio. El evolocumab es un anticuerpo monoclonal que inhibe la PCSK9 y estabiliza la placa ateromatosa.
Jorge D. Olivares-García   +2 more
doaj   +1 more source

Traditsioonilised ja uued ravimid aterogeense düslipideemia ravis [PDF]

open access: yes, 2016
Kardiovaskulaarse riski kahandamise põhialuseks on LDL-kolesterooli sisalduse vähendamine. Statiinid on näidanud hulgalistes juhuslikustatud kliinilistes uuringutes tõhusust ja ohutust ning on muutunud sellega aterogeense düslipideemia valikravimiks ...
Viigimaa, Margus
core   +2 more sources

Patient adherence, compliance, and perspectives on evolocumab for the management of resistant hypercholesterolemia

open access: yesPatient Preference and Adherence, 2018
Constantine E Kosmas,1 Delia Silverio,2 Julio Ovalle,2 Peter D Montan,2 Eliscer Guzman3 1Division of Cardiology, Department of Medicine, Mount Sinai Hospital, New York, NY, USA; 2Cardiology Clinic, Cardiology Unlimited, PC, New York, NY, USA; 3Division ...
Kosmas CE   +4 more
doaj  

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

Methodology and results of cost-effectiveness of LDL-C lowering with evolocumab in patients with acute myocardial infarction in China

open access: yesCost Effectiveness and Resource Allocation, 2023
Background According to the Chinese guidelines for lipid management (2023), evolocumab in combination with statins was recommended as secondary prevention of cardiovascular disease.
Yuansheng Wan   +4 more
doaj   +1 more source

Evolocumab enables rapid LDL-C reduction and inflammatory modulation during in-hospital stage of acute coronary syndrome: A pilot study on Chinese patients

open access: yesFrontiers in Cardiovascular Medicine, 2022
Background and aimsProprotein convertase subtilisin/kexin type 9 (PCSK9) has long been considered a key regulator in lipid metabolism. Its role as a potential player in immune response has recently earned much attention.
Ziwei Ou   +11 more
doaj   +1 more source

Low-density lipoprotein cholesterol lowering therapies: what is on the horizon? [PDF]

open access: yes, 2015
Elevated low-density lipoprotein cholesterol (LDL-C) levels are associated with an increased risk for cardiovascular disease (CVD). Statins have been the cornerstone of lipid therapy to lower LDL-C for the past two decades, but despite significant ...
Figueredo, M.D., Vincent M   +1 more
core   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

open access: yesAdvanced Science, Volume 12, Issue 43, November 20, 2025.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang   +4 more
wiley   +1 more source

Intravascular Ultrasound Findings Associated With Hydrodynamic Contrast Recanalization (HDR) of Coronary Chronic Total Occlusions

open access: yesCatheterization and Cardiovascular Interventions, Volume 106, Issue 5, Page 2880-2889, November 1, 2025.
ABSTRACT Background Hydrodynamic contrast recanalization (HDR) is a novel technique to facilitate wire crossing during chronic total occlusion (CTO) percutaneous coronary interventions (PCI). The mechanisms underlying HDR have not been fully described.
Salman A. Arain   +12 more
wiley   +1 more source

Clinical utility of evolocumab in the management of hyperlipidemia: patient selection and follow-up

open access: yesDrug Design, Development and Therapy, 2017
Dave L Dixon,1 Leo F Buckley,1 Cory R Trankle,2 Dinesh Kadariya,3 Antonio Abbate2 1Department of Pharmacotherapy and Outcomes Science, School of Pharmacy, 2Pauley Heart Center, 3Department of Internal Medicine, School of Medicine, Virginia Commonwealth ...
Dixon DL   +4 more
doaj  

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