Results 91 to 100 of about 7,622,829 (352)

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Models of Chemical Evolution [PDF]

arXiv, 2003
The basic principles underlying galactic chemical evolution and the most important results of chemical evolution models are discussed. In particular, the chemical evolution of the Milky Way galaxy, for which we possess the majority of observational constraints, is described.
arxiv  

On the Galactic chemical evolution of sulfur [PDF]

Astronomy & Astrophysics, 2004
Accepted by A&A, 12 pages.
David L. Lambert, Nils Ryde
openaire   +4 more sources

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

Hydro- Chemical Evolution of Palk Strait Region, Bay of Bengal [PDF]

, 2012
Present analysis was carried out the physico- chemical parameters of two stations such as Thondi and Soliyakudi in the southeast Palk Strait region during the monsoon and post monsoon seasons (November 2008 – March 2009).
Arulpriya, M. (Mani), govindasamy, C. (chinavenkataraman), Meenakshi, V. R. (V), Ruban, P. (Packiasamy)   +3 more
core  

Dynamical and chemical evolution of NGC1569

, 2005
Blue Compact Dwarf and Dwarf Irregular galaxies are generally believed to be unevolved objects, due to their blue colors, compact appearance and large gas fractions.
Aguirre, Aloisi, Aloisi, Alvensleben, Anders, Angeretti, Aparicio, Arnone, Arp, Babul, Blitz, Bradamante, Böhringer, Centurión, Chiappini, Chiappini, Chiappini, Ciotti, D'Ercole, de Heij, de Marchi, Dyson, Ellis, F. Matteucci, Fagotto, Finoguenov, G. Hensler, Gallagher, Gastaldello, Gibson, Greggio, Heckman, Henry, Herwig, Israel, Izotov, Izotov, Izotov, Kennicutt, Kobulnicky, Kobulnicky, Kunth, Köppen, L. Angeretti, Lilly, Loewenstein, Marcolini, Marconi, Marconi, Martin, Martin, Masegosa, Matsushita, Matteucci, Matteucci, Meynet, Momany, Mori, Mori, Mühle, Mühle, Olofsson, Origlia, Ostriker, Ott, Pagel, Pilyugin, Pipino, Pipino, Reakes, Recchi, Recchi, Recchi, Renzini, Renzini, Roediger, Romano, Ruiz-Lapuente, S. Recchi, Searle, Skillman, Spite, Sternberg, Stil, Stil, Tinsley, Tosi, Tozzi, Vallenari, van den Hoek, van Zee, Vílchez, Weidner, Woosley, Östlin   +94 more
core   +1 more source

Chemical Evolution of Protostars [PDF]

Astrophysics and Space Science, 2005
This review discusses the evolution of the chemical composition of the molecular gas throughout the process of star formation. It covers the initial stages of cloud-core formation, gravitational collapse and the formation of the star, the effects of stellar radiation and outflows on the surrounding cloud, and the composition of the circumstellar disk ...
openaire   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Figuring Out Gas and Galaxies In Enzo (FOGGIE). VIII. Complex and Stochastic Metallicity Gradients at z > 2

The Astrophysical Journal
Gas-phase metallicity gradients are a crucial element in understanding the chemical evolution of galaxies. We use the FOGGIE simulations to study the metallicity gradients (∇ Z ) of six Milky Way–like galaxies throughout their evolution.
Ayan Acharyya, Molly S. Peeples, Jason Tumlinson, Brian W. O’Shea, Cassandra Lochhaas, Anna C. Wright, Raymond C. Simons, Ramona Augustin, Britton D. Smith, Eugene Hyeonmin Lee   +9 more
doaj   +1 more source

Chemical evolution of low mass disc galaxies [PDF]

ESP Astrphysics Simposia "Chemical Evolution from Zero to High Redshift", Eds. J. R. Walsh, M. R. Rosa, pg. 154, 1999
We show that the multiphase chemical evolution model reproduces the correlations obtained along the spiral sequence, dwarf galaxies included. However the apparent spatial chemical uniformity observed in some irregular galaxies cannot be reproduced with it. An evolutionary model has been developed and tested to explain flat gradients.
arxiv