Results 31 to 40 of about 14,980 (199)

The Subcellular Proteome of a Planctomycetes Bacterium Shows That Newly Evolved Proteins Have Distinct Fractionation Patterns

Frontiers in Microbiology, 2021
The Planctomycetes bacteria have unique cell architectures with heavily invaginated membranes as confirmed by three-dimensional models reconstructed from FIB-SEM images of Tuwongella immobilis and Gemmata obscuriglobus.
Christian Seeger, Karl Dyrhage, Mayank Mahajan, Anna Odelgard, Sara Bergström Lind, Siv G. E. Andersson   +5 more
doaj   +1 more source

Experimental increase of worker diversity benefits brood production in ants

BMC Ecology and Evolution, 2021
Background The reproductive division of labor of eusocial insects, whereby one or several queens monopolize reproduction, evolved in a context of high genetic relatedness.
Marina N. Psalti, Dustin Gohlke, Romain Libbrecht   +2 more
doaj   +1 more source

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Enzyme-assisted high throughput sequencing of an expanded genetic alphabet at single base resolution

Nature Communications
With just four building blocks, low sequence information density, few functional groups, poor control over folding, and difficulties in forming compact folds, natural DNA and RNA have been disappointing platforms from which to evolve receptors, ligands ...
Bang Wang, Kevin M. Bradley, Myong-Jung Kim, Roberto Laos, Cen Chen, Dietlind L. Gerloff, Luran Manfio, Zunyi Yang, Steven A. Benner   +8 more
doaj   +1 more source

The SoftWipe tool and benchmark for assessing coding standards adherence of scientific software

Scientific Reports, 2021
Scientific software from all areas of scientific research is pivotal to obtaining novel insights. Yet the coding standards adherence of scientific software is rarely assessed, even though it might lead to incorrect scientific results in the worst case ...
Adrian Zapletal, Dimitri Höhler, Carsten Sinz, Alexandros Stamatakis   +3 more
doaj   +1 more source

Energy at Origins: Favorable Thermodynamics of Biosynthetic Reactions in the Last Universal Common Ancestor (LUCA)

Frontiers in Microbiology, 2021
Though all theories for the origin of life require a source of energy to promote primordial chemical reactions, the nature of energy that drove the emergence of metabolism at origins is still debated. We reasoned that evidence for the nature of energy at
Jessica L. E. Wimmer, Joana C. Xavier, Andrey d. N. Vieira, Delfina P. H. Pereira, Jacqueline Leidner, Filipa L. Sousa, Karl Kleinermanns, Martina Preiner, William F. Martin   +8 more
doaj   +1 more source

Molecular evolution of the Chlamydiaceae. [PDF]

International Journal of Systematic and Evolutionary Microbiology, 2001
Phylogenetic analyses of surface antigens and other chlamydial proteins were used to reconstruct the evolution of the Chlamydiaceae. Trees for all five coding genes [the major outer-membrane protein (MOMP), GroEL chaperonin, KDO-transferase, small cysteine-rich lipoprotein and 60 kDa cysteine-rich protein] supported the current organization of the ...
Robin M. Bush, Karin D. E. Everett
openaire   +2 more sources

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA

Nature Communications, 2022
Eukaryotic DNA can be methylated as 5-methylcytosine and N6-methyladenine, but whether other forms of DNA methylation occur has been controversial. Here the authors show that a bacterial DNA methyltransferase was acquired >60 Mya in bdelloid rotifers ...
Fernando Rodriguez, Irina A. Yushenova, Daniel DiCorpo, Irina R. Arkhipova   +3 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source