Molecular characterization of the evolution of phagosomes
Molecular Systems Biology, 2010 Amoeba use phagocytosis to internalize bacteria as a source of nutrients, whereas multicellular organisms utilize this process as a defense mechanism to kill microbes and, in vertebrates, initiate a sustained immune response. By using a large‐scale approach to identify and compare the proteome and phosphoproteome of phagosomes isolated from distant ...
Jonathan Boulais +9 more
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The distributions of protein coding genes within chromatin domains in relation to human disease
Epigenetics & Chromatin, 2019 Background Our understanding of the nuclear chromatin structure has increased hugely during the last years mainly as a consequence of the advances in chromatin conformation capture methods like Hi-C.
Enrique M. Muro +2 more
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Metabolic Cost of a Nutritional Symbiont Manifests in Delayed Reproduction in a Grain Pest Beetle
Insects, 2020 Animals engage in a plethora of mutualistic interactions with microorganisms that can confer various benefits to their host but can also incur context-dependent costs.
Tobias Engl +3 more
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Molecular evolution of enolase.
Acta Biochimica Polonica, 2005 Enolase (EC 4.2.1.11) is an enzyme of the glycolytic pathway catalyzing the dehydratation reaction of 2-phosphoglycerate. In vertebrates the enzyme exists in three isoforms: alpha, beta and gamma. The amino-acid and nucleotide sequences deposited in the GenBank and SwissProt databases were subjected to analysis using the following bioinformatic ...
Irena Kustrzeba-Wójcicka +3 more
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Revista de Química, 2019 Además de sus usos comerciales, los minerales de boro han sido de interés para los investigadores que buscan encontrar una explicación a como se originó la vida en la Tierra.
Roberto Laos, Steven Benner
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Mechanisms of molecular evolution
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000 Both drift and selection are important for nucleotide substitutions in evolution. The nearly neutral theory was developed to clarify the effects of these processes. In this article, the nearly neutral theory is presented with special reference to the nature of weak selection.
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Gene expression atlas of the Colorado potato beetle (Leptinotarsa decemlineata)
Scientific DataThe Colorado potato beetle (CPB) is a major pest of potato crops, known for its remarkable ability to develop resistance to more than 50 pesticides. For decades, CPB has served as a model species for studying insecticide resistance, insect physiology ...
Léonore Wilhelm +2 more
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Morphology Evolution, Molecular Simulation, Electrical Properties, and Rheology of Carbon Nanotube/Polypropylene/Polystyrene Blend Nanocomposites: Effect of Molecular Interaction between Styrene-Butadiene Block Copolymer and Carbon Nanotube. [PDF]
Polymers (Basel), 2021 Otero Navas I +3 more
europepmc +1 more source
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
Nature, 2012 Colorectal tumours that are wild type for KRAS are often sensitive to EGFR blockade, but almost always develop resistance within several months of initiating therapy.
L. Diaz +12 more
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Artificially Expanded Genetic Information Systems for New Aptamer Technologies
Biomedicines, 2018 Directed evolution was first applied to diverse libraries of DNA and RNA molecules a quarter century ago in the hope of gaining technology that would allow the creation of receptors, ligands, and catalysts on demand.
Elisa Biondi, Steven A. Benner
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