Results 71 to 80 of about 8,047,140 (326)

Evolutionary genomics of socially polymorphic populations of Pogonomyrmex californicus

BMC Biology
Background Social insects vary considerably in their social organization both between and within species. In the California harvester ant, Pogonomyrmex californicus (Buckley 1867), colonies are commonly founded and headed by a single queen (haplometrosis,
Mohammed Errbii, Ulrich R. Ernst, Aparna Lajmi, Eyal Privman, Jürgen Gadau, Lukas Schrader   +5 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Molecular Cloud Evolution III. Accretion vs. stellar feedback

, 2010
We numerically investigate the effect of feedback from the ionizing radiation heating from massive stars on the evolution of giant molecular clouds (GMCs) and their star formation efficiency (SFE).
Alan W. Watson, Ballesteros-Paredes, Brunt, Carpenter, Carroll, Caselli, Ceverino, Diaz-Miller, Dib, Elmegreen, Elmegreen, Enrique Vázquez-Semadeni, Evans, Federrath, Gazol, Gilberto C. Gómez, Hartmann, Hartmann, Heitsch, Heitsch, Hennebelle, Hennebelle, Heyer, Hillenbrand, Hillenbrand, Javier Ballesteros-Paredes, Klessen, Klessen, Klessen, Koyama, Koyama, Kravtsov, Kravtsov, Krumholz, Krumholz, Krumholz, Li, Li, Matzner, Matzner, McKee, Nakamura, Nordlund, Ostriker, Ostriker, Padoan, Padoan, Pedro Colín, Rathborne, Rosas-Guevara, Scalo, Spaans, Spezzi, Tan, Tobin, Truelove, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Wada, Wada, Wang, Whitworth, Williams, Yorke   +67 more
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Climate change affects the parasitism rate and impairs the regulation of genes related to oxidative stress and ionoregulation of Colossoma macropomum

Scientific Reports, 2021
Global climate change represents a critical threat to the environment since it influences organismic interactions, such as the host-parasite systems, mainly in ectotherms including fishes.
Jaqueline Custodio da Costa, Samara Silva de Souza, Jonatas da Silva Castro, Renan Diego Amanajás, Adalberto Luis Val   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Imaging the Breakdown of Molecular-Frame Dynamics through Rotational Uncoupling

, 2017
We demonstrate the breakdown of molecular-frame dynamics induced by the uncoupling of molecular rotation from electronic motion in molecular Rydberg states. We observe this non-Born-Oppenheimer regime in the time domain through photoelectron imaging of a
Bucksbaum, Philip H., Natan, Adi, Zipp, Lucas J.   +2 more
core   +1 more source

Early Science with the Large Millimeter Telescope: COOL BUDHIES I - a pilot study of molecular and atomic gas at z~0.2 [PDF]

, 2015
An understanding of the mass build-up in galaxies over time necessitates tracing the evolution of cold gas (molecular and atomic) in galaxies. To that end, we have conducted a pilot study called CO Observations with the LMT of the Blind Ultra-Deep H I ...
Chung, Aeree, Cybulski, Ryan, De la Luz, Victor, Deshev, Boris Z., Erickson, Neal, Fernández, Ximena, Gorkom, Jacqueline van, Haines, Chris, Harrington, Kevin, Hughes, David H., Jaffé, Yara L., Montaña, Alfredo, Montero Castaño, María, Morrison, Glenn E., Narayanan, Gopal, Poggianti, Bianca M., Schloerb, F. Peter, Sánchez, David, Velazquez, Miguel, Verheijen, Marc A. W., Yoon, Hyein, Yun, Min S., Zavala, Jorge A., Zeballos, Milagros   +23 more
core   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Transcriptional profiles of the fish parasite Neoechinorhynchus agilis (Acanthocephala) emphasize energetic stress in males and high cell-division activity in females

BMC Genomics
Background Thorny-headed worms (Acanthocephala) occur worldwide in gnathostome vertebrates feeding on mandibulate arthropods. They can manipulate host behavior, accumulate heavy metals, and have lately gained economic relevance as a pest in fish ...
Camille-Sophie Cozzarolo, Alexandros Vasilikopoulos, Olivier De Thier, Laura Hagemann, Bahram Sayyaf Dezfuli, Karine van Doninck, Holger Herlyn   +6 more
doaj   +1 more source