Results 71 to 80 of about 258,840 (301)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Evolutionary multiobjective optimization: open research areas and some challenges lying ahead
Complex & Intelligent Systems, 2019 Evolutionary multiobjective optimization has been a research area since the mid-1980s, and has experienced a very significant activity in the last 20 years. However, and in spite of the maturity of this field, there are still several important challenges
Carlos A. Coello Coello +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Jixie chuandong, 2005 The method of rigid-body guidance synthesis of adjustable mechanisms for multiple alternation tasks based on evolutionary computation is proposed.The mechanism optimization model of multi-tasks is established,and the global optimization solution will be ...
杨志刚 +3 more
doaj
RFreak-An R-package for evolutionary computation [PDF]
RFreak is an R package providing a framework for evolutionary computation. By enwrapping the functionality of an evolutionary algorithm kit written in Java, it offers an easy way to do evolutionary computation in R.
Nunkesser, Robin
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Interactive Evolutionary Computation for Analyzing Human Awareness Mechanisms
Applied Computational Intelligence and Soft Computing, 2012 We discuss the importance of establishing awareness science and show the idea of using interactive evolutionary computation (IEC) as a tool for analyzing awareness mechanism and making awareness models.
Hideyuki Takagi
doaj +1 more source
Evolutionary Computation Methods and their applications in Statistics
Statistica, 2013 A brief discussion of the genesis of evolutionary computation methods, their relationship to artificial intelligence, and the contribution of genetics and Darwin’s theory of natural evolution is provided.
Francesco Battaglia
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Efficient Computation of Fitness Function for Evolutionary Clustering
Mendel, 2019 Evolutionary algorithms (EAs) are random search heuristics which can solve various optimization problems. There are plenty of papers describing different approaches developed to apply evolutionary algorithms to the clustering problem, although none of ...
Sergey Muravyov +3 more
doaj +1 more source