Results 101 to 110 of about 3,953,318 (310)

Reconciling the upsides and downsides of migration for evolutionary rescue

open access: yes, 2020
A recommendation – based on reviews by Three anonymous reviewers – of the article: Tomasini, M. and Peischl, S. (2020) When does gene flow facilitate evolutionary rescue? bioRxiv, 622142, ver.
Bank, Claudia
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Notes on Evolutionary Game Dynamics [PDF]

open access: yes, 2004
This paper focuses on the mathematical core of evolutionary game dynamics. The biologist Maynard Smith showed that game theory can be applied successfully in biology.
TAKEUCHI, Hiroshi   +2 more
core  

Evolutionary theorizing and modeling of sustainability transitions [PDF]

open access: yes, 2012
This paper argues that evolutionary thinking and modeling can contribute to the emerging research on sustainability transitions and their management.
Frenken, K.   +8 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Correction to: A common gene drive language eases regulatory process and eco-evolutionary extensions

open access: yesBMC Ecology and Evolution, 2021
Prateek Verma   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Implementation, elimination of weakly dominated strategies and evolutionary dynamics [PDF]

open access: yes
This paper is concerned with the realism of mechanisms that implement social choice functions in the traditional sense. Will agents actually play the equilibrium assumed by the analysis? As an example, we study the convergence and stability properties of
Giovanni Ponti, Antonio Cabrales
core  

Population genomics of intrapatient HIV-1 evolution

open access: yeseLife, 2015
Many microbial populations rapidly adapt to changing environments with multiple variants competing for survival. To quantify such complex evolutionary dynamics in vivo, time resolved and genome wide data including rare variants are essential.
Fabio Zanini   +6 more
doaj   +1 more source

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